SI LAB - Glossary 1 Flashcards Preview

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Flashcards in SI LAB - Glossary 1 Deck (50):
1

removal of antibodies from serum by addition of red cells that possess the corresponding surface antigen

absorption

2

antigen that is not genetically determined and is sometimes transient

acquired antigen

3

immunity generated by actual production of antibody by the host in the presence of foreign antigen

active immunity

4

normal serum constituents that increase in the presence of infection, injury, trauma to tissues

acute phase proteins

5

a substance that can increase the specific antibody production to, or the degree of sensitization against antigen by increasing its size or length of survival in the circulation

adjuvent

6

a substance (usually injected with an antigen) that improves the immune response, either humoral or cellular, to the antigen

adjuvent

7

attachment of one substance to the surface of another, in particular, attachment of antibody to specific receptors on a cell surface

adsorption

8

collection into clumps of the cells or particles distributed in a fluid

agglutination

9

antibody capable of causing agglutination with surface antigens

agglutinin

10

an antigen agglutinated or clumped by an agglutinin

agglutinogen

11

system for activating complement beginning at C3 and do not involve a serologic reaction

alternative complement pathway

12

substance in the blood and the lymph serving as one of the active component on the process of cytolysis, the other components being the complement and the cells with antibodies

amboceptor

13

anti-sheep red blood cell antibody that causes hemolysis of sheep red cells in the presence of complement

amboceptor

14

globulin formed in response to exposure to an antigen

antibody (Ab)

15

also known as immunoglobulin

antibody (Ab)

16

any substance that oppose or counteract the action of a complement

Anticomplementary susbtance

17

any substance which, when introduced into the body, stimulates the formation of antibody

Antigen (Ag)

18

union of antibody with its homologous antigen

Antigen-antibody complex

19

an autoantibody directed against a component of the nucleus, commonly found in systemic lupus erythematosus (SLE)

Antinuclear antibody (ANA)

20

serum containing antibody

antiserum

21

an antibody produced against streptolysin O,

antistreptolysin O

22

a hemolysin produced by Group A streptococci

antistreptolysin O

23

ASO meaning

antistreptolysin O

24

antibody produced against self antigen

autoantibody

25

a molecule that behaves as a self antigen

autoantigen

26

lymphocyte from the bursa of Fabricius or an immunoglobulin-forming cell

B-cell

27

substance contained in beef erythrocytes, which is capable of absorbing the heterophil antibodies produced as a result of infectious mononucleosis (IM) and serum sickness

Beef erythrocyte (BE) antigen

28

BE meaning

Beef erythrocyte

29

a protein, not normally present in human blood, appears in a wide variety of inflammatory conditions

C-reactive protein

30

characterized by their ability to react with the C-polysaccharide somatic substance of the pneumococci

C-reactive protein

31

the major system of complement activation that involves all nine components of complement and is initiated by a serologic reaction

Classic complement pathway

32

an agglutinin or hemagglutinin that is active at 4C but not at 37C

Cold agglutinin

33

a humoral mechanism of nonspecific immune response consisting at least 14 components that proceed in a cascading sequence of activation resulting in a cell lysis

Complement

34

fixation of binding of complement in a reaction with antigen and antibody

Complement Fixation

35

monitors day to day accurate performance of the laboratory tests/analyses

Control

36

a substance composed of extract from fresh beef hearts combined with lecithin and cholesterol

Cardiolipin Antigen

37

a hemagglutination test that defines the characteristics of heterophil antibody by guinea pig and beef cell antigens

Davidsohn Differential Test

38

most common procedure for the separation of mononuclear cells

Density gradient centrifugation

39

separation of one substance from the other

dissociation

40

a fluid medium containing antibodies deliberately removed from the red cells

eluate

41

ligand assay in which the label is an enzyme and the binding reagent is an antibody

enzyme immunoassay

42

point of dilution in a serologic reaction in which all the antigen and all the antibody are mutually involved in complexes

equivalence point

43

a specific type of precipitation that occurs over a narrow range of antigen concentration

flocculation

44

aggregation of colloidal particles in a serologic reaction

flocculation

45

heterophil antibody that is stimulated by one antigen and reacts with unrelated surface antigen present on cells from different mammalian species

forssman antibody

46

substance which absorbs the Forssman and serum sickness antibodies

Guinea pig kidney (GPK) antigen

47

flagellar antigens of bacteria

H antigens

48

agglutination or clumping of red blood cells by the antiserum

hemagglutination

49

attachment of antibody to specific receptors on a cell surface

adsorption

50

ANA meaning

antinuclear antibody

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