SI LAB - Glossary 2 Flashcards Preview

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Flashcards in SI LAB - Glossary 2 Deck (46):
1

used in the detection of antibodies involve in the blocking of agglutination of erythrocytes

hemagglutination-inhibition technique

2

ruptured erythrocytes

hemolyzed

3

a substance causing agglutination of red blood cells

hemagglutinin

4

an antibody capable of causing the lysis of dissolution of red cells with the consequent release of hemoglobin

hemolysin

5

the lysis of red blood cells by specific antibody and serum complement

hemolysis

6

inflammation of liver caused by virus or other agent

hepatitis

7

an antibody produced in response to one antigen that will react with a second antigen genetically unrelated antigen

heterophil antibody

8

antigen that is broadly distributed in nature

heterophil antigen

9

virus that caused AIDS

Human Immunodeficiency Virus (HIV)

10

solution in which has a concentration greater than the system with which it is compared

hypertonic solution

11

a process by which the activity of serum complement is nullified

inactivation

12

acute infectious disease caused by Epstein-Barr virus characterized by fever, pharyngitis, and lymphadenopathy

infectious mononucleosis (IM)

13

acute infectious disease in which there is a moderate leukocytosis due to abnormal mononuclear cells

infectious mononucleosis (IM)

14

outside the body; observable in a test tube

In vitro

15

observable in a test tube

in vitro

16

within the living body

in vivo

17

molecule that combines with specific complementary configurations of the binding agent (e.g. receptors, proteins, or antibody)

ligand

18

creation of a stable preparation of a biologic material by rapid freezing and dehydration of the frozen product under high vacuum

lyophilization

19

an antibody which causes dissolution or lysis of cells

lysin

20

an antigen-antibody reaction in w/c the reactive effect of a particular antigen is nullified by a specific antibody

neutralization

21

surface somatic antigen of bacteria

O antigen

22

antibody that attaches to a cellular or particular antigen rendering it susceptible to phagocytosis

opsonin

23

hemagglutination resulting from antibodies that are directed against antigens absorbed to their erythrocyte surface

passive hemagglutination

24

liquid portion of unclotted blood

plasma

25

weak or irregular antigen-antibody reaction occurring when a great excess of antigen is exposed to a serum containing a relatively low titer of antibody

postzone reaction

26

an Ag-Ab rxn in w/c a soluble antigen is caused to settle out by the action of specific antibody (precipitin)

precipitation

27

a negative or weak reaction occurring when serum containing an extremely high titer of antibody is exposed to a relatively small amount of antigen

prozone reaction

28

failure of serologic reaction to occur in high concentration of antibody

prozone reaction

29

clumping of cells caused by agents other than antibodies

pseudoagglutination

30

an atom with an unstable nucleus that spontaneously emits radiation as it decays to a stable nucleus

radioisotope

31

antibody-like substance produced by the body in response to certain types of tissue invasion and destruction

reagin

32

found in varying small amounts normally, but is usually increased in syphilis, malaria, etc

reagin

33

a progressively higher dissolution of a substance arranged in a definite sequence or series

serial dilution

34

branch of biology which concerns itself with antigens and antibodies and their relationships

serology

35

a condition wherein cells are coated with incomplete (blocking or univalent) specific antibody

sensitized

36

the detection of a specific antibody in the serum of an individual in whom the antibody was previously undetectable

seroconversion

37

fluid portion after the blood clots

serum

38

special affinity between an antigen and its corresponding antibody

specificity

39

an assay in which one of the reactant is bound to a surface

solid radioimmunoassay

40

an enzyme that dissolves clots by converting plasminogen to plasmin

streptokinase

41

thymus-derived lymphocyte responsible for cell-mediated hypersensitivity

T-lymphocyte (T-Cell)

42

expression of the highest dilution of serum w/c gives a visible reaction

titer

43

measurement of light transmitted through a suspension of particles

turbidimetry

44

agglutination of red blood cells by a virus

viral hemagglutination

45

antibody (or agglutinin) or hemagglutinin that is active at 37C but not at 4C

warm agglutinin

46

reduction in the electrical charge of a red cell when it is suspended in a high ionic strength colloidal medium (albumin)

zeta potential

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