Skeletal Muscle

Question 1

what type of muscle is being described?

many nuclei, striations, very big, has voluntary control, and is somatic innervation

Answer 1

Skeletal Muscle

Question 2

what type of muscle is being described?

striations, nuculi, intercalated discs, no voluntary control, innervation is autonomic

Answer 2

Cardiac muscle

Question 3

what type of muscle is being described?

no striations, singular nuclei, no voluntary control, innervation is autonomic

Answer 3

Smooth muscle

Question 4

What are functions of skeletal muscle (5)

Answer 4

1. movement and posture
2. support of soft tissue
3. regulate entry of food and exit of waste products
4. thermoregulation

**Allow us to breathe by contraction of the diaphragm

Question 5

What do muscle fibers begin as?

Answer 5

Myoblasts

Question 6

What is the term called when some myoblasts do not fuse together?

Answer 6

Myosatellites

Question 7

Connective tissue that is superficial and covers the whole muscle

Answer 7

Epimysium

Question 8

Connective tissue that is intermediate and covers muscle fascicles

Answer 8

Perimysium

Question 9

Connective tissue that is deep and covers individual fibers

Answer 9

Endomysium

Question 10

Middle of sarcomere is called

Answer 10

M line

Question 11

end of sarcomere is called

Answer 11

Z disc

Question 12

this is where no overlap is present from the thin and thick filaments. Just the thick filament

Answer 12

H zone

Question 13

the entire length of the thick filament is called the

Answer 13

A band

Question 14

No overlap from the thick and thin filaments. Just the thin filaments are present

Answer 14

I band

Question 15

What is the long protein called that attaches to the Thick Filament

Answer 15

Titin or Connectin

Question 16

What is the thick filaments predominant protein?

Answer 16

Myosin

Question 17

What is the thin filaments predominant protein?

Answer 17

Actin

Question 18

What is the protein called that covers myosin binding sites on g-actin molecules

Answer 18

Tropomyosin

Question 19

What is it called: three separate proteins; binds tropomyosin and Calcium

Answer 19

Troponin

Question 20

What is the basic unit of a contractile muscle fiber called

Answer 20

sarcomere

Question 21

what are the two main PROTEIN filaments that a sarcomere is composed of. which are active structures responsible for muscle contraction

Answer 21

Actin and Myosin

Question 22

Region between 2 z discs

Answer 22

Sarcomere

Question 23

How is muscle contraction produced?

Answer 23

Neurotransmitter, ACh gets to the muscle cell, ATP is produced, which elevated Calcium levels, and contraction occurs

Question 24

What percentage do Myofibrils account for inside the cell?

Answer 24

80%

Question 25

What are myofibrils surrounded by? | Think of mani's marker and glove example

Answer 25

Sarcoplasmic Reticulum

Question 26

What is the sarcoplasmic reticulum example Mani gave us?

Answer 26

Glove wrapped around many markers, which resembled the myofibrils and the SR

Question 27

the pump that transports calcium ions from the cytoplasm into the sarcoplasmic reticulum

Answer 27

SERA

Question 28

T-Tubules are ____ of the cell and sit ___ of the SR

Answer 28

Inside, On top

Question 29

myofibrils contain:

Answer 29

thick and thin filaments

Question 30

Thick filaments are contained of myosin which then have ( ) conformation

Answer 30

high or low

Question 31

The myosin head allows for what to bind?

Answer 31

ATP and actin binding site

Question 32

What is the rod shaped protein that sits on top of myosin binding sites?

Answer 32

Tropomyosin

Question 33

Trimetric complex (TnI,TnC,TnT) are from

Answer 33

Troponin

Question 34

do thick and thin filaments change shape? if no, what do they do

Answer 34

No they slide over one another (Sliding Filament Theory)

Question 35

Myosin pushes ___ filament over the ____ filament

Answer 35

thin over the thick

Question 36

When the sliding of the filaments occur. What disappears?

Answer 36

H zone

Question 37

How long will the cross bridging continue?

Answer 37

As long as the calcium levels remain high

Question 38

how are sliding filaments caused?

Answer 38

A series of attachment and detachment cycles of myosin heads on actin binding sites

Question 39

in a resting state does TnC have calcium bound to it?

Answer 39

no

Question 40

how does Rigor Mortis occur? (Stiffness after death)

Answer 40

due to the depletion of ATP in muscles, therefore causing actin and myosin unable to detach from one another (Constant contraction)

Question 41

During sliding filament theory -- as the area shrinks what happens to the bands/zones

Answer 41

H and I zones get smaller A zone does not change HOW? Calcium