Skeletal Muscle Relaxants Flashcards Preview

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Flashcards in Skeletal Muscle Relaxants Deck (8):
1

Atracurium undergoes rapid spontaneous breakdown (___________ elimination) to form ____________, lowers seizure threshold.

Hoffman
laudanosine

2

Nondepolarizing blockers
- surmountable blockers that prevent action of _______ at the skeletal muscle end plate
- effects reversed by ________________ (neostigmine)

Nondepolarizing blockers
- surmountable blockers that prevent action of ACh at the skelatal muscle end plate
- effects reversed by cholinesterase inhibitors

3

SE: recurarization
Relatively contraindicated in MI

Tubocurarine (metabolites have same effect as tubocurarine)

4

Reverse effects with neostigmine
Metabolized by pseudocholinesterase

Mivacurium

5

Undergoes elimination in bile (shorter action than those eliminated by the kidneys)
Muscle relaxation is potentiated by naked anesthetics, aminoglycosides, and quinidine

Vecuronium (think Vecuronium Vile)

6

Nondepolarizing blocker with most rapid onset time
Sugammadex is a novel reversal agent

Rocuronium (ang bilis, parang si Rocky Rocacurva)

7

For lethal injection, euthanasia

Pancuromium

8

Depolarizing neuromuscular blocker
Metabolized by pseudocholinesterase

Succinylcholine

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