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dermatology > Skin cancer > Flashcards

Flashcards in Skin cancer Deck (50)
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1

skin cancer - types and MC

1. basal cell carcinoma (BCC) (MC)
2. Squamous cell carcinoma
3. Melanoma

2

MC skin cancer

basal cell carcinoma (BCC)

3

basal cell carcinoma (BCC) of the skin is found in (area of the body and classic location)

sun exposed areas
classic location: upper lip

4

basal cell carcinoma (BCC) of the skin - behavioural

1. locally invasive
2. RARELY metastasizes

5

basal cell carcinoma (BCC) of the skin - macroscopic appearance

pink, pearly nobules, commonly with telengectasias, rolled borders, central crusting or ulceration

6

basal cell carcinoma (BCC) of the skin - colour

pink

7

basal cell carcinoma (BCC) of the skin - borders

rolled borders

8

basal cell carcinoma (BCC) of the skin - central

crusting or ulceration

9

basal cell carcinoma (BCC) of the skin - present (to the doctor) as

nonhealing ulcer with infiltrating growth or as a scaling plaque (superficial BCC)

10

basal cell carcinoma (BCC) of the skin - Histology

clusters of darkly staining basaloid cells with a palisade arrangement of nuclei at the periphery of the clusters

11

second MC skin cancer

Squamous cells carcinoma (SCC)

12

Squamous cells carcinoma (SCC) of the skin is associated with (risk factors)

1. excessive exposure to sunlight
2. immunosuppression
3. arsenic exposure

13

Squamous cells carcinoma (SCC) of the skin commonly appears on

1. face 2. lower lip 3. ears 4. hands

14

Squamous cells carcinoma (SCC) of the skin - behavioural

- locally invasive
- may spread to lymph nodes
- metastasize: uncommon

15

Squamous cells carcinoma (SCC)of the skin - histopathology

keratin pearls

16

Squamous cells carcinoma (SCC) of the skin - macroscopic appearance

ulcerative red lesions with frequent scale.

17

Squamous cells carcinoma (SCC) of the skin is associated with

chronic draining sinuses

18

Squamous cells carcinoma (SCC) of the skin - precursor lesion

Actinic keratosis

19

Actinic keratosis appearance

scaly plaque, hyperkeratotic
(small, rough, erythematous or brownish papules or plaques)

20

keratoacanthoma - definition

keratoacanthoma is a variant (well differentiated squamous cell carcinoma that develops rapidly (4-6 weeks) and may regress spontaneously over months

21

keratoacanthoma - develops rapidly (how long)

4-6 weeks

22

keratoacanthoma - present as a

cap-shaped tumor filled with keratin debris

23

Melanoma - metastasis?

significant risk

24

melanoma - tumor marker

S-100

25

melanoma - risk factors

1. sunlight exposure
2. fair-skinned persons are at high risk

26

melanoma - .... correlates with risk of metastasis

depth of tumor

27

melanoma - depth of tumor correlates with risk of metastasis

risk of metastasis

28

melanoma - in clinical examination, look for

mnemonic ABCDE
Asymmetry, Border irregularity, Color variation, Diameter > 6 mm, Evolution over time

29

melanoma - how many subtypes

at least 4 different types

30

melanoma - some subtypes

1. superficial spreading
2. nodular
3. lentigo maligna
4. acral lentiginous