Skin pathophysiology: eczema, dermatitis, psoriasis 1 Flashcards Preview

Stage 4 Skin > Skin pathophysiology: eczema, dermatitis, psoriasis 1 > Flashcards

Flashcards in Skin pathophysiology: eczema, dermatitis, psoriasis 1 Deck (7)
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1

What is the definition of atopic?

Related to allergic response

2

Which gene is important for encoding epidermal structural proteins?

Filaggrin gene - in chromosome 1

3

What is the role of filaggrin gene?

Produces protein that binds to keratin fibres in the epidermis of skin

Keratin molecules glue barrier together to form tight sheet

4

Define dermatitis

Chronic, relapsing inflammation of the skin

5

Broad term for eczema?

Dermatitis (umbrella term)

6

Name the TWO hypotheses associated with development of atopic dermatitis

1. Immunological hypothesis

2. Skin barrier hypothesis

7

Functions of the skin. 6 items.

Regulate BODY TEMPERATURE

Stores BLOOD

Synthesises VITAMIN D

Excrete and absorbs substances

DETECTS cutaneous sensations

PROTECTS body from external environment