When are NSAIDs used in SLE treatment?
Pain and inflammation caused by various SLE symptoms
NSAID frequency
Acute or chronic, can be scheduled or PRN
NSAID complications
GI, cardiac, renal complications
Renal complications of NSAIDs
Drug-induced AKI
GI complications of NSAIDs
Increase GI bleed risk- add on a PPI PRN
What happens if a patient needs to take prophylactic ASA and also taking an NSAID?
Take ASA 1 hour before NSAID or after the NSAID depending on the duration of action of the NSAID
Bleeding risk and NSAIDs
Can increase bleed risk in patients who have clotting abnormalities