Sleep Flashcards by Kirilee Wagner

Q

Sleep is mediated by which nucleus?

A

Ventral pre-optic nucleus (VLPO)

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Q

How does the VLPO induce sleep?

A

By inhibiting (GABA) wake-promoting neurons

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Q

Role of the locus coeruleus in sleep

A

Wake-on, noradrenalinergic

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Q

Neurotransmitters involved in wakefulness

A

Noradrenaline
Histamine
Serotonin
Orexin

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Q

What is the result of a loss of orexin neurons?

A

Narcolepsy

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Q

Role of adenosine in sleep

A

A metabolite that promotes sleep

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