Small Intestinal Disorders and Investigation Flashcards Preview

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Flashcards in Small Intestinal Disorders and Investigation Deck (17):
1

What are the common symptoms of small intestinal disorders?

Weight loss
Increased appetite (due to malabsorption)
Steatorrhoea

2

Why is steatorrhoea a common symptom in small intestinal disorders?

Fat is the first thing to stop being absorbed from small intestine due to malabsorption -> higher fat content being passed out in stool

3

Give 6 signs of specific deficiencies arising from small intestinal disorders

Anaemia

Deficiency in:
Vitamin B12
Ca
Mg
Vitamin D
Vitamin A
Vitamin K
Vitamin B
Thiamine
Niacin
Vitamin C

4

What are the non-specific signs of specific small intestinal illnesses?

Clubbing
Scleroderma
Apthous ulceration

5

Dermatitis herpetiformis is a cutaneous manifestation of

coeliac disease

6

What is the typical presentation of dermatitis herpetiformis?

Blistering, intensely itchy skin, appears commonly on the scalp, shoulders, elbows and knees

7

Why are blisters occurring as a result of dermatitis herpetiformis rarely seen?

As patients scratch them while asleep

8

Give 5 investigations that can be done to determine small intestinal structure

Small bowel biopsy via endoscopy
Barium meal
White cell scan
CT
MRI enterography
Capsule enterography

9

What is coeliac disease?

A common disease
Sensitivity to Gliadin fraction of gluten, produces an inflammatory response causing partial or subtotal villous atrophy

10

What would be seen in the serology of a patient with coeliac disease?

Anti-endomysial IgA
Anti-tissue transglutaminase

11

Give 5 conditions associated with coeliac disease

Dermatitis herpetiformis
Insulin dependent diabetes mellitus
Autoimmune thyroid disease
Autoimmune hepatitis
Primary biliary cirrhosis
Autoimmune gastritis
Sjogren syndrome
IgA deficiency
Downs syndrome

12

What are the possible complications of coeliac disease?

Refractory coeliac disease
Small bowel lymphoma
Oesophageal carcinoma
Colon cancer
Small bowel adenocarcinoma

13

Give 6 causes of malabsorption

Inflammation
Infection
Infiltration
Impaired motility
Iatrogenic
Pancreatic

14

Give an example of an inflammatory cause of malabsorption

Crohn's disease
Coeliac disease

15

Give an example of an infection causing malabsorption

Tropical sprue
HIV
Giardia lamblia
Whipple's disease - tropheryma whippelii

16

Give an example of impaired motility which would cause malabsorption

Systemic sclerosis
Diabetes
Pseudo-obstruction

17

Give an example of a pancreatic cause of malabsorption

Chronic pancreatitis
Cystic fibrosis