Specialized Tissues, Stem Cells And Tissue Renewal II Flashcards Preview

Molecular Biology Exam 3 > Specialized Tissues, Stem Cells And Tissue Renewal II > Flashcards

Flashcards in Specialized Tissues, Stem Cells And Tissue Renewal II Deck (22):
1

Sensory Cells

Apical vs Basal End

Apical
- Has specialized structures that detects the EXTERNAL Stimulus
- Converts into a change in membrane potential


Basal
- Makes SNAPSE with the neurons that relay the sensory information to specific sites in the brain

2

What system has the LEAST capacity to Self repair or regenerate?

CNS

3

Characteristics of Sensory Epithelia

- Covers tissues of the nose, ears and eyes (sensory)

- Derived from ECTODERM

- sensory cells act as TRANSDUCERS
(Convert signal from envt into ELECTRICAL signals to the CNS)

- Well CONSERVED

4

Relay stations in the brain are called what?

Glomeruli

5

Cells of the olfactory system

1. Olfactory neurons
- With protruding Cilia

2. Supporting cells
- hold neurons in place

3. Basal Cells
- Connect to Basal Lamina

6

Olfaction in Neurodegenerative Disorders

1. Parkinson’s
- Reduced sense of smell precedes clinical symptoms


2. Alzheimer’s
- Correlates to a loss of smell

7

How many days does it take for a Newt to regenerate a limb?

25 days

8

Average Glomeruli per olfactory bulb in mice?

1800

9

Sensory cells of the

1. Nose

2. Ears

3. Eye

1. Olfactory sensory Neurons

2. Auditory HAIR cells

3. Photoreceptors

10

Where do olfactory neurons expressing the same odorant receptors converge?

Their AXONS converge on the SAME Glomerulus

11

Regeneration is common in ______organisms

Non-Mammalian

- Ex: Newt

12

Regeneration of Newt Limb

- Differentiated muscle cells in the stump REENTER the Cell Cycle

- De-Differentiate

- Become Embryonic cells

- Proliferate to form a Limb Bud

- Regenerate mussing limb

13

Differential abilities of Neuro-spheres

1. Can stay as stem cells

2. Differentiate into Neurons

3. Differentiate into BOTH Neurons and Glial cells

14

Stem Cells in Hippocampus

- Involved in learning and MEMORY formation

- Continuous turnover of cells in the hippocampus

- 1400 fresh neurons are generated every day

15

Odorant receptor genes: Dogs Vs Humans

Dogs - 1000

Human - 350

16

T/F: Each olfactory Neuron expresses only ONE of the odorant genes and responds to only ONE class of Odorant

True

17

What areas of the brain posses stem cells?

1. Ventricles of the forebrain

2. Hippocampus

18

How long do individual olfactory neurons survive?

1 month

19

What kind of receptor is a olfactory receptor

G protein Coupled Receptor

20

How many classes of oderant molecules can an olfactory receptor bind?

1

- May include a variety of odor molecules

21

Influx of what causes an action potential in the nose?

Na+ And Ca2+

22

Characteristics of Neurospheres

- Cultures established from self renewing regions of the brain

- Clusters of Neural stem cells, Neural cells and Glial cells

- Can be PROPAGATED through several generation