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Flashcards in Spleen Deck (16):
1

2 specific immune responses the spleen does

Antigen processing & Ab production by splenic lymphocytes

2

where are the Ab made?

white pulp

3

Which Ab is most largely produced in spleen

IgM

4

The most useful imaging to determine splenic size and splenic injury

CT with IV and oral contrast. BUT US doesnt req radiation so usually preferred if possible.

5

Best method for searching for accessory spleen? (when splenectomy has not lead to full recovery of pt condition)

Radionucleotide scan

6

What is Kehr sign?

pain at the top of the left shoulder referred from diaphragmatic irritation after splenic rupture

7

What are indications for complete splenectomy

emergency with unstable pt, or grade V level of injury (Completely shattered spleen or hilar vascular injury with devascularization)

8

when partial splenectomy, the % of spleen that must remain for adequate immune function?

50%

9

Name 2 hemolytic anemias caused by metabolic problems; and can they be fixed with splenectomy?

G6PD deficiency and pyruvate kinase deficiency. NO.

10

Tx for autoimmune hemolytic anemias?

Corticosteroids and splenectomy if unresponsive

11

the only condition in which thrombocytopenia is primary issue and the tx is splenectomy?

ITP

12

Are ecchymosis a sign of low PLTs?

Not usually. That would indicate a coag disorder.

13

In hypersplenism assoc with splenomegaly which happens first anemia or thrombocytopenia?

thrombocytopenia

14

post splenectomy thrombocytosis is pharm tx how?

hydroxyurea

15

Common trend in WBC s/p splenectomy

Inc to 15000-20,000 for 5-7d is normal. Longer than this indicates infection

16

S&S of pancreatic injury/pancreatitis occur how long after splenectomy?

5-7d