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Flashcards in spread of cancer Deck (15)
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1

three modes of transport for cancer

1. lymph (may enter venous system)
2. through the blood (difficult to survive if enters arterial system)
3. angiogenisis- they grow on along the capillaries,to get oxygen, get larger and larger or travel through the vascular network

2

initiation

change in DNA by a carcinogen

3

promotion

some happens so the cancer cells are not destroyed
p53 and tp53 cells are associated with poor prognosis

4

progression

designates the process which the tumors get bigger cancer goes from bad to worse

5

benzene

light yellow liquid that is highly flammable long term effects, long term exposure leads to leukemia

6

tobbaco causes what

30% of all cancer death, head, neck, lung, pancreatic, cervical and bladder cancer
synergistic effects with alcohol, asbestos, uranium, viruses

7

vinyl chloride

makes PVC, dont microwave or burn plastic

8

heavy carcinogenic metals

arsenic
beryllium
cadmium
nickel compounds
hexavalent chromium

9

bacterial carcinogenisis

relationship between helicopbacter pylori and mucosa associated with lymph tissue- barrets esophigitis

10

BRCA 1 and BRCA 2

breast cancer gene `

11

APC gene

polyposis coli, hereditary colorectal cancer- both alleles need to be mutated

12

WTI- wilms tumor

malignant renal tumor acocunting for 6% of chilhood cancer. 80% of children are diagnosed before age 5. loss of supressor gene WT1

13

physical carcinogens

agents damage cancer suppressor genes
UV radiation
Ionizing radation- Xrays and radiation therapy
Asbestos- fibrous material

14

viral carcinogenesis

hep B
human T cell luekemia virus
epstien barr virus- highly though of cause of lymphoma, nasopharyngeal cancer, hodgkins lymphoma

15

cancer prevention

diet rich in fruits and veggies
decrease fat in diet
increase physical activity
decrease UV exposure
safe sex/HPV vaccine
stop smoking
alcohol in moderation