stat power Flashcards

(24 cards)

1
Q

Define statistical power.

A

Probability of correctly rejecting a false null hypothesis (1 − β).

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2
Q

Type II error rate is denoted by (a)_____

A

(a) β

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3
Q

List the four quantities inter-related in power calculations.

A

α (significance level), β (Type II error), effect size, sample size.

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4
Q

What is an a priori power analysis?

A

Power calculation performed during study planning to determine the required sample size.

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5
Q

Post-hoc power analysis is generally discouraged. Why?

A

A non-significant result does not prove H₀; calculating power afterwards conditions on an unknown effect and is misleading.

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6
Q

Differentiate manipulative and observational experiments.

A

Manipulative: researcher deliberately alters factors;

Observational: researcher measures variables as they occur naturally.

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7
Q

Give an example of a treatment and block in an observational study.

A

Treatment: smoking-status categories; Block: participant groups sharing the same treatment level.

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8
Q

Explain why sample sizes that are too large can be unethical in clinical studies.

A

Participants may face risk unnecessarily when fewer subjects would suffice to detect the effect.

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9
Q

According to Cohen’s convention, what d values correspond to small, medium, and large effect sizes?

A

0.2 (small), 0.5 (medium), 0.8 (large).

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10
Q

Using G*Power, which three inputs would you supply to compute required N for a t-test?

A

α (e.g., 0.05), desired power (e.g., 0.80), expected effect size d.

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11
Q

Name two ways to increase power aside from increasing N.

A

Use a larger α (if justified) or reduce measurement noise (increase precision).

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12
Q

The relationship among α, β, and effect size for fixed N is (a)___ -reducing one inflates (at least) one of the others.

A

(a) inverse

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13
Q

What graphical tool helps visualise trade-offs among power, N, and effect size?

A

Power curve (plot of power vs. sample size for a specified effect).

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14
Q

When is a one-tailed test justified in power analysis?

A

Only when effects in the opposite direction are impossible or biologically meaningless a priori.

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15
Q

Give a rule of thumb for desired power in biomedical research.

A

0.80 (80 %) is commonly accepted; higher if consequences of Type II error are severe.

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16
Q

What parameter in ANOVA drives the non-centrality parameter used in power calculations?

A

The ratio of between-group variance to within-group variance (signal-to-noise).

17
Q

Describe sequential stopping rules in the context of power/ethics.

A

Interim analyses allow ending a trial early for efficacy or futility, safeguarding participants.

18
Q

What is the mnemonic “#events ≈ 50 / (d²)” used for?

A

Quick estimate of required events in survival analysis given effect size d (log-hazard ratio).

19
Q

Name one assumption common to most power formulas that, if violated, inflates Type I error.

A

Independence of observations.

20
Q

Power plot axes:

A

X-axis: sample size (N); Y-axis: power (1 − β).

21
Q

Software besides G*Power capable of power analysis?

A

Minitab (add-on), SPSS (add-on), or R packages (pwr, simr).

22
Q

In a two-group t-test with d = 0.8, α = 0.05, desired power = 0.80, how many total participants are needed?

A

≈ 52 participants (26 per group).

23
Q

True or False: Lowering α from 0.05 to 0.01 increases power (all else equal).

A

False – lowering α makes it harder to reject H₀, so power decreases.

24
Q

Power = 1 − (?)