Stem Cell Origins (19) Flashcards Preview

CEDB30004 Stem Cells in Development and Regeneration > Stem Cell Origins (19) > Flashcards

Flashcards in Stem Cell Origins (19) Deck (11):
1


What is a feature of the distal tip found in C. elegans?
a. It keeps germ cells in a meiosis stem cell like state
b. It down-regulates delta-notch signalling
c. It up-regulates mitosis specific genes
d. It is present in the intestine



c. It up-regulates mitosis specific genes

2

What is not a feature of differentiation of GSCs in the drosophila ovary?
a. The terminal filament secretes the UPD cytokine
b. BMP repressed BAM in GSCs
c. UPD activates BMP in cap cells
d. As GSCs move away from the niche, BMP signalling is up-regulated

d. As GSCs move away from the niche, BMP signalling is up-regulated

3

What is not a feature of differentiation of GSCs in the drosophila testis?
a. Once far enough away from BMP signalling, differentiation occurs immediately
b. Hub cells secrete UPD which activates BMP in cyst stem cells
c. BAM is repressed in GSCs due to BMP signalling
d. Differentiation leads to the formation of spermatogonia

a. Once far enough away from BMP signalling, differentiation occurs immediately

4

What is true about BAM mutants?
a. Loss of bam in the ovary represses proliferation of GSCs
b. Loss of bam in the testis leads to proliferation of spermatogonia
c. Loss of bam in the ovary down-regulates BMP signalling
d. Loss of bam in the testis leads to proliferation of GSCs

b. Loss of bam in the testis leads to proliferation of spermatogonia

5

What is involved in the division of drosophila intestinal stem cells?
a. They only give rise to more intestinal stem cells
b. They directly divide into enterocytes and enteroendocrine cells
c. They can produce enteroblasts which give rise to specific intestinal cell types
d. The process depends on UPD and BAM signalling

c. They can produce enteroblasts which give rise to specific intestinal cell types

6

What is a feature of sponges?
a. Cells form tissues and organs
b. Layers contain the same cell types
c. There is extensive neuronal networks and epithelial tissues
d. The cells are arranged loosely and mesenchyme like

d. The cells are arranged loosely and mesenchyme like

7

What is a feature of a Piwi family protein?
a. They are absent in human haematopoietic stem cells
b. Archeocytes and Choanocytes express one and have stem cell properties
c. It is found in stem cell populations of cnidarian
d. It is unique to choanoflagelletes

b. Archeocytes and Choanocytes express one and have stem cell properties

8

What is not a feature of plant meristems?
a. They are stem cell populations
b. They contain zones of cell division, elongation, differentiation
c. The meristem is maintained by Wuschel-expressing cells
d. Meristem secretes Clavata3 which increases the size of the Wuschel domain

d. Meristem secretes Clavata3 which increases the size of the Wuschel domain

9

• C. Elegans can be males or hermaphrodites and the only dividing cells are found in the gonads

. T

10

• Drosophila females have germ line stem cells found in the ovary.

T

11

• The loss of APC has no effect in drosophila.

F