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Flashcards in STIs Deck (58):
1

What are some of the symptoms during seroconversion of HIV

Flu-like
Fever
nights sweats
weight loss

2

What is the time frame of seroconversion for HIV

process from being negative to positive takes about 3 weeks to 6 months

3

What does AIDS=

CD4

4

What is the initial screening test for HIV?

ELISA (>99.9% sensitivity)

5

What is the confirmatory test for HIV?

western blot test for confirmatory

6

What is the normal CD4 count

>800

7

What are the 2 most important indicators of HIV

Absolute CD4 count and the viral load

8

What is the viral load testing?

PCR: quantatative copies of HIV-branched DNA or RNA
results correlate closely with profession to HIV
should ideally be zero or undetectable

9

What do you give to HIV patients in prevention of pneomocystis jiorvecci ?

Daily bacterim

10

How do you prevent drug resistance to AART therapy?

take at the SAME TIME every day

11

What is chancroid

Hemophilud ducreyi, a gram negative bacillus

12

What should you test for in a patient with chancroid

syphilis and HSV

13

s/sx of chancroid

Women- usually asymptomatic
Men- Single or multiple superficial PAINFUL ulcer surrounded by an erythematous hall
Ulcers may be necrotic or severely erosive
UNILATERAL BUBO

14

How do you diagnose chancroid?

By exclusion
If not T.Pallidum or HSV (by inspection or culture) and coexisting tender inguinal lymphadenopathy, is suggestive of chancroid. Definitive is by morphology

15

How do you treat chancroid

Azithromycin (zithromax) 1 gram by mouth x1 dose OR
Ceftriaxone (rocephin) 250mg IMx1 dose OR
Ciprofloxacin (cipro) 500mg by mouth twice daily for 3 days

16

What is sensitivity

The degree to which those who have a disease screen/test positive

17

What is specificity?

The degree to which those who do not have the disease with screen/ test negative

18

What are the 3 causes of dysuria

chlamydia
gonorrhea
UTI

19

What are the causes of dysparunia

chlamydia
PID
menopause
trich

20

What is the lab for chlamydia

Culture is the most definitive (takes 3-9days)
Enzyme immunoassay (EIA) methods are preferred (low cost, fast results )

21

What is the treatment for chlamydia?

Azithromycin (zithromax) 1 gram by mouth x1 dose OR
Doxy 100mg PO BID x7days
Alternatives include erythromycin, ofloxacin, levofloxacin

22

What are the reportable STIs

Gon, chlamydia, syphillis

23

What is the other name for genital warts?

Condyloma acuminata

24

What virus causes genital warts?

HPV

25

What are the symptoms of genital warts?

single or multiple soft, fleshy, papillary or sessile PAINLESS keritinized growths around the anus, vaginal penile urethra or perineum

26

How do you diagnose genital warts?

clinical presentation
ASCUS or SIL on PAP smear
colposcopy if flat lesions
biopsy of at risk for cervical intraepithelial neoplasia (CIN)

27

tx for condyloma acuminata

keratolytic agents: podophyllin (pododerm), trichloroacetic acid (TCA) or bichloracetic acid (BCA)
Referral for cryo, laser….

28

What does Gardasil prevent and age range

types 6, 11, 16, 18
females and males aged 9-26

29

What is the most common symptom of Gonorrhea

80% of females are asymptomatic

30

how will the discharge for gonorrhea be different from chlamydia

will be mucopurulent and green

31

Diagnostics for gonorrhoeae

Gram stain of discharge smear shows gram - diplococci and WBC
Cervical culture for N gonorrhoeae using modified thayer-martin media

32

Treatment of gonorrh

ceftriaxone (rocephin) 250mg IM x1 dose to treat gone
PLUS azithromycin (zithromax) 1 gram orally x1 dose to over chlamydia
Report to health department

33

When are the Hep B vaccinations administered?

0,1, and 6 months

34

What do yo give in a Hep B exposure

HBIG 0.06 ml/kg in a single dose within 14 days of exposure

35

What kind of immunity is HBIG

passive immunity

36

What kind of immunity are toxoids

active immunity

37

What are some symptoms of gonorrhea in males?

dysuria
frequency
white/ yellow penile discharge
testicular pain
N/V

38

What are the s/sx of herpes

initial: Fever, dysuria, PAINLESS/puritic ulcers for usually 12 days
recurrent: less painful/ puristic ulcers for usually 5 days

39

What is the management of herpes

NO cure
symptomatic treatment with drying and antipyretic agents
Acyclovir for topical , oral, Iv
Valacyclovir: especially useful for asymptomatic viral shedding of HSV2

40

What are the s/sx of lymphgranuloma Venereum

2-3mm PAINLESS vesicle, BUBO, or non-indurated ulcer
REGIONAL ADENOPATHY follows in approx 1 month and is the most common finding
stiffness and aching in groin followed by unilateral swelling of the inguinal region

41

Diagnosis of lymphogranuloma venereum

definitive diagnosis requires isolating C. Trachomatis from a specimen

42

treatment of lymphogranuloma venereum

doxy 100mg BID x21 days
aspirate bubos to prevent ulcerations

43

What does molluscum contagioum look like?

Lesions are 1-5mm, smooth, firm, shiny flesh colored to pearly white papules

44

What is the offender in syphilis?

Treponema pallidum

45

What does the primary stage of syphilis look like?

Chancre is PAINLESS
Indurated ulcer
located at the site of exposure

46

What does the secondary stage of syphilis look like?

Flu-like symptoms
Highly variable rash on palmar and plantar surfaces: mucous patches
lymphadenopathy
maliase
anorexia
alopecia
arthralgias

47

What does the latent stage of syphilis look like?

symptomatic but seropositive

48

What does the tertiary stage of syphilis look like?

Leukoplakia
Cardiac insufficiency
aortic aneurysm
meningitis
hemiparesis
hemiplegia

49

What is the initial serological test for syphilis?

VDRL/RPR

50

What are good confirmatory tests for syphilis?

treponemal:
Fluorescent treponemal antibody absorption (FTA-ABS)
Microhemagglutination assay for antibody T pallidum

51

Treatment for primary, secondary, or early syphilis less than 1 year

PCN G 2.4million units IM

52

Treatment for late, latent, indeterminate length, and tertiary stage

PCAN G IM weekly x 3 weeks

53

tx for syphilils if PCN allergic

doxy 100mg PO BID or erythromycin 500mg PO QID

54

what are early signs of HIV/ serconversion?

fever, nightsweats, weightloss

55

what is the preferred method of testing for chlamydia

enzyme immunoassay; its low cost and only takes about 30-120 minutes

56

what are the diagnostic tests for herpes

papanicolau tzanck testing

57

what stage of syphilis does lymphadenopathy appear

secondary

58

what occurs in the primary stage of syphilis?

painless chancres