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Flashcards in Straight Definitions Deck (42):
1

Complete virus particle that consists is the extracellular infective form of a virus

Virion

2

Mature virus

Virion

3

Infectious particle smaller than a virus consisting of only a circular RNA molecule

Viroid

4

Particle that lacks a protein coat and is associated with plant diseases

Viroid

5

Basic subunit protein in the capsid of a virus

Capsomere

6

Capsid + virus RNA/DNA/genome =

Nucleocapsid

7

Capsomeres and nucleic acid are wound together to form a spiral tube

Helical symmetry

8

Solid with 12 corners, 20 facets, and 30 edges

Icosahedral

9

Has a triangulation number to describe the relation between the number of pentagons and hexagons of the structure

Icosahedral

10

Visions are composed of several parts, each with separate shapes and symmetries

Complex symmetry

11

Antigenic shift that involves a single gene segment

Recombination

12

Exchange of nucleotide sequences between different but usually closely related viruses

Recombination

13

Antigenic shift that involves a segmented genome

Reassortment

14

The most important mechanism for high genetic diversity in viruses with segmented genomes

Reassortment

15

Process by which a naked virus exits the host cell following replication

Lysis

16

Process by which an enveloped virus exits the host cell following replication

Budding

17

Viruses that acquire their envelope from the host cell plasma membrane are released via _____

Budding

18

Viruses that acquire their envelope from the host cell ER are released by vesicles that migrate to the plasma membrane in a process called _____

Exocytosis

19

A disease that has extended beyond its origin and involved the bloodstream to travel to other areas of the body

Disseminated infection

20

An infection that affects the entire body

Systemic infection

21

Presence of viruses in the blood

Viremia

22

The specificity of a virus for a particular host tissue

Tropism

23

Viruses that can replicate in more than one host organ or tissue

Pantropic virus

24

The dose of the virus required to cause death in 50% of animals

LD50

25

Accumulation of viral components, result from degenerative changes in the cell, or crystalline aggregates of virions in a host cell during viral infection

Inclusion bodies

26

The constant presence of a viral disease within a given geographic area or population group

Endemic

27

Occurrence of more cases of viral disease than expected in a given area or among a specific group of animals/people over a particular period of time

Epidemic

28

Refers to peaks in disease incidence that exceed the endemic/enzootic baseline or expected incidence of disease

Epidemic

29

Viral disease occurring occasionally, singly, or in scattered instances, and in an irregular and haphazard manner

Sporadic

30

Virus epidemic occurring over a very wide area (several countries/continents) and usually affecting a large portion of the population

Pandemic

31

The number (%) of deaths among the clinically ill animals

Case-fatality rate

32

The number (%) of animals in a population that die from a particular disease over a specified period of time

Mortality rate

33

The virus cycles between humans and insect vectors

Urban cycle

34

The virus is transmitted between non-wild or domestic animals and the primary or accessory insect vector

Rural/epizootic cycle

35

The natural transmission of virus between wild animals and primary insect vectors

Sylvatic/enzootic cycle

36

Host from which infectious agents are not transmitted to other susceptible hosts

Dead-end/incidental host

37

Host does not develop sufficient viremia to be picked up by insect vectors

Dead-end/incidental host

38

Host in which the level of virus can become high enough that an insect vector that feeds on it will probably become infectious

Amplifying host

39

Vaccines produced from naturally occurring attenuated viruses

Live-attenuated vaccine

40

Serial propagation in tissue culture, in a heterologous species, and cold-mutants

Live-attenuated vaccines

41

Virulent virus formulated w/chemical adjuvant to enhance the immune response

Inactivated/killed vaccine

42

Vaccine with only a portion of the pathogen in the vaccine

Subunit vaccine