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Flashcards in Study Guide 6 Deck (29)
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1

What are the diagnostic tools for CNS disorders?

- Clinical exam
- CT
- MRI T1
- MRI T2
- Functional MRI
- PET scan
- EEG

2

Why would a CT be chosen over an MRI?

- faster than MRI
- better for bone, chest, abdomen, spine, pelvis, tumors
- better dx of hemorrhagic vs. occlusive CVA

FAST

3

CT uses:

Radiation

4

Both types of MRIs use:

Magnets and radio waves

5

How long do MRIs take?

30 mins

6

What are MRIs best for visualizing?

- soft tissue
- tendons
- joints
- ligaments

7

Types of MRI are different with this

Relaxation time

8

MRI T1 uses (relaxation time)

Longitudinal relaxation time

9

MRI T2 uses (relaxation time)

Transverse relaxation time

10

Which MRI is used with gadolinium contrast?

MRI T1

11

What does gadolinium contrast allow with an MRI T1?

- see vascular changes
- normal vessels
- disruption of BBB

12

Transverse relaxation time (T2) is good for:

- brain anatomy
- CSF spaces
- most brain lesions
- early hemorrhage

13

What does a functional MRI depend upon?

Blood oxygenation level

14

What does a functional MRI look at?

- functional activation of brain during tasks
- can be used in research
- track changes in ability to perform motor, visual, cognitive tasks

15

What does a PET scan visualize?

cellular activity via regional blood flow

16

PET scan is good for:

- organ function study
- regional density of some NTs
- can be used to look at functional brain activation

17

What does EEG look at?

Amplitude of transmissions

18

EEG is used to assess

- hearing
- coma functioning
- brainstem function

**Brainstem auditory evoked potential**

19

What does this look like: CSF, T1-weighted

Dark

20

What does this look like: CSF, T2-weighted

Bright

21

What does this look like: white matter, T1

Light

22

What does this look like: white matter, T2

Dark gray

23

What does this look like: cortex, T1

Gray

24

What does this look like: cortex, T2

Light gray

25

What does this look like: fat, T1

Bright

26

What does this look like: fat, T2

Light

27

What does this look like: inflammation, T1

Dark

28

What does this look like: inflammation, T2

Bright

29

What are the goals of pharmacological control of CNS damage/disorder?

- change production and uptake of NT
- selective interaction with NT receptors
- modulation of synthesis, release, reuptake, and degradation of NTs
- mediation of NT release by action at presynaptic receptors

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