Superficial, Cutaneous and Subcutaneous fungal infections Flashcards Preview

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Flashcards in Superficial, Cutaneous and Subcutaneous fungal infections Deck (12)

What are the clinical classifications of human mycoses?

Mycoses are classified as superficial, cutaneous, subcutaneous, or systemic (deep) infections depending on the type and degree of tissue involvement and the host response to the pathogen.


What are the three genera of fungi that make up the dermatophytes?

Three common species:


Descibe the typical lesion of tinea

Annular lesion, which spreads centrifugally, may be sharply defined, displays peripheral activity and tends to heal in the centre


Where does tinea occur, and how does the lesion change depending on body site?

In and around hair: can cause hair loss, and scales but still annular
Horny layer of skin: usually the well defined circular lesion
Warm, moist skin folds: in is lichenified with a small amount of scale
Just under nails: nail becomes thick, crumbly and discoloured


What does a nail infected with a dermatophyte look like?

Thick, crumbly and discoloured, usually around the distal and lateral nail borders


What is the appearance of tinea capitis?

Gradual appearance of round patches of dry scale, alopecia, or both


What is the appearance of tinea kerion?

"Kerion celsi" - deepest dermatophyte infection of the scalp, and is accompanied by marked cervical lymphadenopathy and fever, as well as severe local inflammation, with tender erythematous exudative swelling and hair loss


What is the appearance of cutaneous candidiasis?

Scaling and maceration of the skin
Red, itchy rash
Potentially blisters/pustules


What is the appearance of mucous membrane candidiasis?

Classical discharge: milky white, thick discharge with curd-like chunks, inflamed and swollen mucosa. Will also be painful and itchy


What are the features constituting a sporotrichoid infection?

Small papule on periphery of trauma site
Gradual development of non-healing ulcer
Pus filled red swellings moving up the limb


Name three organisms that produce sporotrichoid lesions

-Sporothrix Schenckii
-Bacteria including Nocardia
-Mycobacterium marinum


What does pityriasis look like microscopically?

Fungal elements, short sausage shaped elements and groups of yeast-like cells in "spaghetti and meatballs" arrangement

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