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Pharmacology > Supplements > Flashcards

Flashcards in Supplements Deck (30):
1

Echinacea use

Immune: increase in immune cell counts (monocytes, phagocytes, NTKs,) and general immune modulation. (not found to be true)

Anti-inflammatory: reduce edema after application of topical irritant

Antiviral: against herpes simplex, flu ; antibacterial against strep, flu, legionella. Not found to be true

2

Echinaecea adverse effects

Flu-like symptoms with intravenous use

GI symptoms with oral use

3

Echinaecea interactions

Avoid use in immunosuppressed patients

4

Garlic use

CV: inhibits cholesterol biosynthesis

Endocrine: regulates glucose homeostasis

Anti-microbial

Antineoplastic

5

Garlic adverse effects

body odor
bleeding
nausea
hypotension

6

Garlic interactions

with anti-coagulant medications

7

Gingko use

CV: increase blood flow

Antioxidant

CNS: dementia and insufficiency

Allergic and asthmatic bronchoconstriction, ED, tinnitis,

8

Gingko adverse effects

GI, headache, insomnia

9

Gingko interactions

Anti-platelet and anti-coagulation
Sedative
Should not be used with people with seizures

10

Ginseng use

Modulate immune function
Increase levels of NTs
Anti-oxidant
Anti-inflammatory
Lower glucose levels after feeding
Anti-cancer

11

Ginseng adverse effects

Vaginal bleeding
Mastaglia
CNS stimulation leading to anxiety and insomnia
Nausea
HTN

12

Ginseng interactions

Psychiatric medications
Warfarin
immunocompromised populations

13

Milk thistle use

Treat acute and chronic viral hepatitis, alcohol liver disease, and liver injury

Anti-inflammatory

Inhibits TNF-alpha to reduce tumor initiation and promotion

Induction of lactation

14

Milk thistle adverse effects

None

15

Milk thistle interactions

None

16

St. Johns Wort use

Anti-depressant
PMDD
Anti-viral
Anti-carcinogenic

17

St. Johns Wort adverse effects

Photosensitization
Mania

18

St. Johns Worst interaction

Drugs with similar mechanisms can cause serotonin syndrome

19

Saw Palmetto use

Benign prostatic hyperplasia by inhibiting 5-alpha reductase

20

Saw Palmetto adverse effects

GI, rhinitis, fatigue, headache, decreased libido

21

Saw Palmetto interactions

None

22

Coenzyme Q use

Antioxidant
HTN
Heart failure
Ischemic heart disease
Replace levels lost due to statin

23

Coenzyme Q adverse effects

Rare

24

Coenzyme Q interactions

Warfarin

25

Glucosamine use

Improvements in overall mobility, range of motion, and strength in patients with osteoarthritis

26

Glucosamine adverse effects

None

27

Glucosamine interactions

Warfarin

28

Melatonin use

Jet lag
Insomnia
Contraception

29

Melatonin adverse effects

Rare

30

Melatonin interactions

Other drugs metabolized by CYP1A2