Sympathetic Agonist Drugs (Sympathomimetics) Flashcards Preview

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Flashcards in Sympathetic Agonist Drugs (Sympathomimetics) Deck (26):
1

isoproterenol

B1 and B2 agonist

2

DA at low doses

D1 and D2 agonist

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DA at medium doses

B1 and B2 agonist

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DA at high doses

A1 and A2 agonist

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Dobutamine

B1 > B2 agonist

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indications for dobutamine

used in stress tests and sometimes in heart failure--> increases HR and contractility

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Phenylephrine

A1 selective agonist

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phenylephrine uses

pupilary dilation and nasal decongestion

9

albuterol, levalbuterol, salmeterol

B2 > B1 agonist
used for asthma

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Advantage of levalbuterol over albuterol and salmaterol

less tachycardia (more B2 specific)

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terbutaline

B2 > B1 agonist

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main use of terbutaline

tocolysis--> inhibits uterine contraction

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Clonidine

A2 agonist--> decreses NE release; used for HTN

*issues with rebound hypertension

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alpha-methyldopa; main use

A2 agonist--> used in pregnancy-induced HTN, like pre-eclampsia

15

3 indirect sympathetic agonist

1. amphetamines
2. Ephedrine
3. cocaine

16

amphetamine and ephedrine MOA

release stored catecholamines

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cocaine MOA

inhibits catecholamine reuptake

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given in nebulizer for asthma

albuterol or levalbuterol

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DOC for anaphylaxis

Epinephrine

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MC first line agent for septic shock or cardiogenic shock

NE

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NE

A1, A2, B1 agonist

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Epinephrine

A1, A2, B1, B2 agonist

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given subQ for asthma, etc

terbutaline--> remember, also mainly used for tocolysis, also given subQ for this = rapid onset

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used by ENT to constrict nasal vessels

Phenylephrine, sometimes cocaine

25

Ritrodine

B2 selective agonist--> can be used to reduce premature uterine contractions

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advantage of using clonidine or alpha methyldopa for HTN

HTN with kidney dz--> decrease hypertension with no decrease in blood flow to kidney

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