Synaptic Physiology Flashcards Preview

Physio 1st LE > Synaptic Physiology > Flashcards

Flashcards in Synaptic Physiology Deck (15)
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1
Q

Point of communication between 2 neurons or a neuron and an effector organ

A

Synapse

2
Q

Short process emanating from the soma

A

Dendrites

3
Q

Long process emanating from the soma

A

Axon

4
Q

Terminal portion of an axon where mitochondria and RER are typically found

A

Presynaptic neuron

5
Q

Neurotoxin that targets synaptobrevin to block the fusion of synaptic vesicles

A

Tetanus

Botulium B,D,F,G

6
Q

Neurotoxin that targets SNAP-25 to block the fusion of synaptic vesicles

A

Botulinum A/E

7
Q

Neurotoxin that targets Syntaxin to block the fusion of synaptic vesicles

A

Botulinum C1

8
Q

Temporary depolarization of postsynaptic membrane cause by the flow of positively charged ions into the postsynatic cell

A

Excitatory Postsynaptioc Potential (EPSP)

9
Q

Temporary hyperpolarization of postsynaptic membrane caused by the flow of negatively charged ions into the postsynaptic cell

A

Inhibitory Postsynaptic Potential (IPSP)

10
Q

Postsynaptic potentials of 2 or more neurons combined at the same time (type of summation)

A

Spatial summation

11
Q

When a cell receives input that are close in time, they are also added together (type of summation)

A

Temporal summation

12
Q

Pharmacologic agents and toxins that affect NMJ:

Blocks the binding of Ach with receptors

A

Curare

Alpha bugarotoxin

13
Q

Pharmacologic agents and toxins that affect NMJ:

Inhibits the release of Ach

A

Botulinum toxin

14
Q

Pharmacologic agents and toxins that affect NMJ:

Clumps the Ach vesicles causing the massive release of Ach

A

Black widow spider toxin

15
Q

Pharmacologic agents and toxins that affect NMJ:

Irreversible inactivation of Ach

A

Organophosphates