Synaptic transmission and neuronal integration Flashcards

1
Q

What is the communication between 2 neurons

A

Synaptic transmission

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2
Q

What is the communication location between neuron and muscle cell

A

Neuromuscular plate

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3
Q

What is the neurotrasmitter at a Neuralmuscular junction

A

Acetylcholine (ACH)

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4
Q

Describe ionic mechanisms

A

transient opening of ion channel permeable to both Na+ and K+ non selective cationic channels

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5
Q

Describe excitatory synapses

IN the CNS

A

depolarisation - decrease in negativity

in the postsynaptic membrane

= Excitatory postsynaptic potential

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6
Q

Describe Inhibitory synapses

IN the CNS

A

hyperpolarisation- increase in negativity

in the postsynaptic membrane

= Inhibitory postsynaptic potential

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7
Q

State the Excitatory synapses Neurotranmitters

A

Glutamine acid

acetylcholine

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8
Q

What transient channels open in a excitatory synapses

A

Na/ K

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9
Q

State the Inhibitory synapses

A

GABA or glycine

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10
Q

What are the inhibitory synapse channels that open

A

K+

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11
Q

What are the two types of synapsis within the CNS

A

Excitatory synapses

Inhibitory synases

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12
Q

what are the two classifications of Neurotransmitters

A

Slow molecule transmitter

Neuropeptide

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13
Q

Describe Neuropeptide

A

Large molecule

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14
Q

Examples of small molecule neurotransmitters

A

amino acids
acetylcholine
amines

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15
Q

Describe Neuropeptides

A

slow/ modulate other neurotranmitters/ Indirect/ diffuse

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16
Q

Examples of Neuropeptides

A

Neuropeptide Y
Enkephaln
Substance
Kisspeptin

17
Q

What are the factors influencing synaptic action

A

type of neurotransmitter/ neuromodulator

type of receptor/ channel complex

amount of neurotransmitter receptor

18
Q

Describe the neurotransmitter inactivation

A

diffusion

enzymatic degradation

re-uptake

19
Q

state the neurotransmitter inactivation transporters location and examples

A

located in the presynaptic membrane

involved glutatmate transporter

dopamine transporter

or serotonin transporter