systemic sclerosis/scleroderma Flashcards
1
Q
what is systemic sclerosis?
A
-a multisystem autoimmune disease characterised by vasculopathy, autoimmunity and fibrosis
2
Q
what are the different types of systemic sclerosis?
A
- Diffuse
- Limited
- Scleroderma
3
Q
what is affected in diffuse systemic sclerosis?
A
-skin involvement on extremities above and below elbows (plus face and trunk)
4
Q
what is affected in limited systemic sclerosis?
A
-skin involvement on extremities only below elbows and knees (plus face)
5
Q
what is scleroderma?
A
-the tightening and fibrosis of the skin
6
Q
what causes the fibrosis in systemic sclerosis?
A
-excess collagen deposition
7
Q
what medication should patients be put on if they’re having renal complications due to systemic sclerosis?
A
ACEI
