TABLES for - PP - Neoplasms introduction 2016 Flashcards Preview

PATHOmorphology Final Prep 2016/2017 > TABLES for - PP - Neoplasms introduction 2016 > Flashcards

Flashcards in TABLES for - PP - Neoplasms introduction 2016 Deck (19):
1

Epithelial:
(Immunohistochemistry)

- Cytokeratins
- EMA
- PSA

2

Lymphoid:
(Immunohistochemistry)

LCA

3

Melanocytic:
(Immunohistochemistry)

HMB45, MelanA, S100

4

Muscle:
(Immunohistochemistry)

- Desmin
- Actin

5

Glial:
(Immunohistochemistry)

- GFAP
- S100

6

Neuroendocrine:
(Immunohistochemistry)

- Chromogranin A
- Synaptophysin
- Insulin

7

Vascular:
(Immunohistochemistry)

- CD34
- CD31
- FVIII

8

Histiocytic:
(Immunohistochemistry)

CD68

9

Embryonal antigens:
(Immunohistochemistry)

- AFP
- CEA

10

RB:
(Inherited cancer syndromes)

retinoblastoma retinoblastoma

11

P53:
(Inherited cancer syndromes)

Li Fraumeni syndrome (various tumours)

12

p161NK4A:
(Inherited cancer syndromes)

melanoma

13

APC:
(Inherited cancer syndromes)

familial adenomatous polyposis/colon cancer

14

NF1, NF2:
(Inherited cancer syndromes)

neurofibromatosis 1 and 2

15

BRCA1, BRCA2:
(Inherited cancer syndromes)

breast and ovarian breast and ovarian tumour

16

MEN1, RET:
(Inherited cancer syndromes)

multiple endocrine neoplasia 1 and 2

17

MSH2, MLH1, MSH6:
(Inherited cancer syndromes)

hereditary nonpolyposis colon cancer

18

Familial cancers:

familial clustering of cases but role of inherited predisposition not clear
* Breast cancer (not linked with BRCA1 or BRCA2)
* Ovarian cancer
* Pancreatic cancer

19

Inherited autosomal recessive syndromes of defective DNA repair:

- Xeroderma pigmentosum
- Ataxia teleangiectatica
- Fanconi anemia