Teratogens associated with human malformations Flashcards
(15 cards)
cataracts, glaucoma, heart defects, hearing loss, tooth abnormalities
rubella virus
microcephaly, visual impairment, intellectual disability, fetal death
cytomegalovirus
microphthalmia, microcephaly, retinal dysplasia
Herpes simplex virus
Skin scarring, limb hypoplasia, intellectual disability, muscle atrophy
varicella virus
Hydrocephalus, cerebral calcifications, microphthamia
toxoplasmosis
Microcephaly, spina bifida, cleft palate, limb defects
x-rays
Limb defects, heart malformations
thalidomide
Heart malformations
SSRIs
Growth retardation, fetal death
ACE inhibitors
Fetal alcohol syndrome (FAS), short palpebral fissures, maxillary hypoplasia, heart defects, intellectual disability
alcohol
Isotretinoin embryopath: small abnormally shaped ears, mandibular hypoplasia, cleft palate, heard defects
isotretinoin (vitamin A)
Neurological symptoms similar to those of cerebral palsy
organic mercury
Neurological symptoms similar to those of cerebral palsy
lead
Various malformations; heart and neural tube defects most common
Maternal diabetes
neural tube defects, heart defects, omphalocele
maternal obesity