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Pharmacology > Terms To Know > Flashcards

Flashcards in Terms To Know Deck (11):
1

Pharmaceutics

The study of how different dosage forms influence pharmacokinetics and pharmacodynamics

2

Pharmacokinetics

The study of what the body does to the drug

3

4 steps of how your body uses drugs

Absorption (from administration site into the Bloodstream)
Distribution (from bloodstream to site of action)
Metabolism (biochemical transformation of a drug into an inactive or potent metabolite)
Excretion (elimination of drugs from the body)

4

What are the different sites of metabolism

Liver (primary)
Skeletal muscle
Kidneys
Lungs
Plasma
Intestinal mucosa

5

First-Pass effect

Metabolism of a drug from the liver to circulation

Some drugs MUST go thru this to be effective. Some drugs can be harmful to the liver from this effect.

6

Bioavailability

A measure of the extent of drug absorption

0-100%

100% means all of the drug gets used and is more potent.

7

Pharmacodynamics

What drugs do to the body

8

Receptor theory

Cellular mechanism used to change body processes

9

Receptor

Structural component of a cell where drugs bind

Made of protein

10

Do all drugs use receptors

No some connect with cell function and change membrane excitability or stability

Usually nerve or muscle cells

11

Agonist

Drugs capable of binding to receptors and cause cellular response

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