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Pharmacology 2 Past Qu. > Test 4 > Flashcards

Flashcards in Test 4 Deck (10):
1

List the side effets of potentiated sulphonamides.
(12)

- Nephrotoxicity, crystalluria.
- Dysbacteriosis--> K-avitaminosis in poultry.
- Keratoconjunctivitis
sicca if administered long term.
- Allergy ( dobermann)
- Haematological changes.
- Sulf- methaemoglobinaemia.
- Sulfaquinoxaline.
- Aditoprim, baquiloprim hepatotoxic.
- Precipitate with vit C or methionine.
- ø given to dehydrated patients.
- Eq not given orally--> results in death.
- Combined with alpha 2 agonist--> lethal cardiac toxicity.

2

What is drilled well disinfectant + how is this method prepared?

100g Ca-hypochlorite or 300 cm3 bleach should be solved in 1L of H2O + poured into well.

3

What generation is used for anaerobes? Give e.g.

- 4th generation e.g pradofloxacin, moxifloxacin.

4

List 4 of the 2nd generation fluroquinolones.

- Enro-, Marbo-, Dano-, Iba-, Di-, Orbifloxacin.

5

What is atropine used for?
(5)

- Parasympatholytic effect: Mydriasis + relaxation of ciliary fibers.
- Used in diagnostic examination of eye.
- Affect on the parasymp nervous system.
- For treatment of bradycardia.

6

List the side effects of fluoroquinolones.
(5)

- Epiphysis- cartialge damaging capability ø applicable for young animals + children.
- Retinopathy in cat.
- CNS effects ( depression + excitation).
- Dysbacteriosis.
- Renal insufficiency--> dosage adjustment is required.

7

What is dug well disinfectant + how is this method prepared?

- 30g fresh Ca-hypochlorite or 100cm bleach/1m H2O, solved 0.3 l H2O, poured into well.
- After mixing, leave for 24hrs rest + smell.
- If Cl is smellable it's good.
- If there is no Cl smell we should repeat it until we reach the CL smell.
- Then the H2O from the well should be discarded, till the smell of the Cl cannot be smelled.

8

List 4 short acting sulphonamides.

- Sulfa- dimidine, -diazine, -methoxasole, -chlorpyridazine, -doxine, -salazine, -quinoxaline, -chlorpyrazine.

9

Indication of metronidazole.
(6)

- gingivitis, parodontitis, oral cavity infections.
- Anal sacculitis.
- Pseudomembranous colitis.
- Giardiosis.
- Trichomonosis, hexamitosis, amoebioasis.
- Histomonosis.

10

Name an intestinal disinfectant.

Sulfaguanidine.