Tests of Renal Function and Hydration Status Flashcards Preview

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Flashcards in Tests of Renal Function and Hydration Status Deck (36):
1

What is the active form of vitamin D

1,25 dihyroxycalciferol

2

What is the active form of vitamin D

1,25 dihyroxycalciferol

3

Typical urine volume

750-2000ml/24hrs

4

Oliguria

5

Anuria

6

Polyuria

>3000

7

Normal plasma urea conc

3-8mmol/L

8

What is the problem with plasma urea tests

Not specific, causes include protein intake, tissue trauma, dehydration, kidney filtration, kideny reabsorptiona nd exretion

9

What are the causes of increase in plasma urea

GI bleed, trauma, renal hypoperfusion= all decrease renal blood flow and extracellular fluid volume)
Acute renal impairment, chronic renal disease and post renal obstruction

10

Normal plasma creatinine levels

50-140micromol/l

11

How is plasma creatinine influenced by GFR?

As GFR decreases, plasma creatinine increases

12

In which patients is GFR measured in

Kidney donors or to assess drug dosages

13

What is the equation used to measure creatinine clearance?

Creatinine clearance= (conc. creat in urine x vol of urine)/conc of creat in plasma (micromoles)

14

What is the equation used to measure creatinine clearance?

Creatinine clearance= (conc. creat in urine x vol of urine)/conc of creat in plasma (micromoles)

15

Typical urine volume

750-2000ml/24hrs

16

Oliguria

17

Anuria

18

Polyuria

>3000

19

Normal plasma urea conc

3-8mmol/L

20

What is the problem with plasma urea tests

Not specific, causes include protein intake, tissue trauma, dehydration, kidney filtration, kideny reabsorptiona nd exretion

21

Describe the effect renal oliguria has on the sodium conc in the urine

High sodium conc int eh urine

22

Normal plasma creatinine levels

50-140micromol/l

23

How is plasma creatinine influenced by GFR?

As GFR decreases, plasma creatinine increases

24

In which patients is GFR measured in

Kidney donors or to assess drug dosages

25

What renal function test tests the ability of the kidneys to clear technecium 99?

GFR

26

What is the equation used to measure creatinine clearance?

Creatinine clearance= (conc. creat in urine x vol of urine)/conc of creat in plasma (micromoles)

27

Normal creatinine clearance

100-130ml/min

28

What effect does a low GFR have on creatinine clearance

Decreases

29

What 4 things does eGRF take into account

creatining, age, sex and ethnicity

30

Treatment for stage 5 chronic kidney disease

Dialysis/transplantation

31

Describe the plasma/urine urea ratio and sodium conc in the urine for pre renal oliguria

High P/U urea ratio
Low sodium conc in urine

32

In what type of oliguria is the GFR low, ADH high and urine sodium conc. low?

Pre-renal

33

Causes of pre-renal oliguria

Decreased renal perfusion
Dehydration
Haemorrhage-hypotension
Renal artery damage

34

Describe the effect renal oliguria has on the sodium conc in the urine

High sodium conc int eh urine

35

What is the problem in renal oliguria?

Nephrons are unable to resorb sodium

36

Causes of renal oliguria

Intrinsic damage (tubular necrosis)
Chronic infection
Immulogical damage-SLE
Toxic damage-drugs, heavy metals, poisons