Tetracycline

Question 1

Tetra is contraindicated in

a. children
b. pregnancy
c. renal failure
d. all

Answer 1

d. all

Question 2

The bacterial resistance to tetra is due to

a. alteration of drug binding site
b. alteration of dehydrofolate reductase
c. inactivation of drug by enzyme
d. decreased uptake of drug by bacteria

Answer 2

c. inactivation of drug by enzyme

There are 3 major
mechanism
1. Decrease
influx/enhance efflux
2. Displacement of target
3. Enzymatic inactivation

Question 3

Distinct advantage that tetra hv over penicillin is

a. no S/E
b. safer for pregnant women
c. wider range of bacterial activity

Answer 3

c. wider range of bacterial activity

Question 4

tetra chelates with

a. ca salt
b. mg salt
c. all

Answer 4

c. all

Question 5

Which is not S/E of tetra?

a. increase risk of sunburnwith sun exposure
b. yellow teeth
c. bone deformities in fetus
d. thyroiditis

Answer 5

d. thyroiditis

Question 6

Which is excreted via bile?

a. doxycycline
b. demeclocycline
c. tetra

Answer 6

a. doxycycline

Question 7

The tetracycline is used in the treatment of

urinary tract infection
bronchitis
tonsillitis
pneumonia

Answer 7

urinary tract infection