The biological approach to explain OCD Flashcards Preview

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Flashcards in The biological approach to explain OCD Deck (12):
1

The genetic explanation to OCD

Stronger Biological Component. Individuals inherited specific genes from parents related to the onset of OCD.

2

Function of COMT GENE

Production of COMT/Regulates production of dopamine

3

How does the COMT predispose a person to OCD?

Variant. Tukel et al suggest the COMT gene lowers the production of COMT - Increases production of dopamine.

4

Function of SERT gene/ 5-HTT

Affects the transport of serotonin creating lower levels. These changed levels of serotonin affect OCD.

5

OCD is a...

Polygeneic disorder

6

DSM

OCD has genetic biological cause but genetically speaking it’s not the sole reason why an individual develops OCD. The genes possessed creates genetic vulnerability. Environmental trigger and the gene is required to cause OCD.

7

The genes associated with OCD affect...

Levels of key transmitters

8

What level of dopamine lead to OCD?

High levels

9

Schechtman

Conducted an animal study to, found high doses of drug enhanced dopamine levels, movement of animals resembled compulsive behaviours in OCD patients

10

What level of serotonin lead to OCD?

Low levels

11

Piggott

An antidepressant drug which increased the levels of serotonin activity reduced the symptoms of OCD

12

How does increased activity in the Orbitofrontal Cortex lead to OCD?

The OFC sends ‘worry’ signals to the thalamus. These are normally suppressed by the caudate nucleus but, if damage, then the thalamus is alerted and confirms the worry to the OFC.