The Molecular Basis of Inheritance (2) Flashcards

1
Q

DNA is a _____ ______ made of ______

A

Nucleic acid, nucleotides

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2
Q

What bonds form between nucleotides

A

Hydrogen bonds

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3
Q

How many parts is DNA made of

A

3

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4
Q

What are the three parts of DNA

A

Nitrogenous bases phosphate groups and a five carbon sugar

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5
Q

Nitrogenous bases have a chemical like structure that allow them to

A

Absorb UV light

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6
Q

What are the chemicals in nitrogenous bases that allow them to absorb UV light beneficial for

A

This allows scientists to measure the amount of DNA by measuring the amount of light it absorbs at a wavelength of 260 nm

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7
Q

Purine

A

Two ring nitrogenous base

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8
Q

Pyrimidine

A

One ring nitrogenous base

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9
Q

What bases are purines

A

Adenine and guanine

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10
Q

What bases are pyrimidines

A

Cytosine and thymine

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11
Q

Where are the covalent bonds in a DNA molecule

A

The nucleotides of a strand of DNA are joined by covalent bonds between the sugar one nucleotide and the phosphate group of the next

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12
Q

Chargaff’s rule

A

Adenine always bonds with thymine and guanine always bonds with cytosine

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13
Q

How did Chargaff create his rule

A

He discovered his rule because of the percentages of adenine and thymine and guanine and cytosine are always almost identical in any sample of DNA

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14
Q

Rosalind Franklin

A

Used x-ray diffraction to study the structure of the DNA moleculef

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15
Q

What was Rosalind Franklins job

A

X-ray crystallographer 

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16
Q

Who did Franklin work under

17
Q

How did Franklin get a picture of DNA

A

She purified a large amount of DNA strand of the DNA fiber is in a thin glass tube until they were parallel and shot powerful concentrated x-ray PMs and recorded the scattered patterns of the extras on a film

18
Q

What does x-ray diffraction pattern reveal

A

It revealed a helix structure of two strands with nitrogenous bases in the center

19
Q

Helix

A

Extended Spiral chain of units in a protein nucleic acid and other macromolecules

20
Q

James Watson and Francis crick

A

Made 3-D models of DNA with cardboard and wire by using Franklins x-ray pattern they made a double helix in which two strands of nucleotide sequences were wound around each other

21
Q

Watson and crick published their work in the paper true or false

22
Q

What was the name of Watsons book

A

The double helix

23
Q

The double helix model explains ______ rule and how the two strands of DNA are held together

A

Chargaff’s rule

24
Q

Antiparallel

A

Two strands of DNA run in opposite directions

25
Nitrogenous bases are hold together by
Hydrogen bonds
26
Why are the hydrogen bonds between Nitrogenous bases very important
Because the bond is weak which allows for the DNA to break which is very important for one of its functions
27
Base pairing
Nearly perfect fit between A and T and G and C
28
The sides of DNA are made of
Alternating deoxyribose and phosphate
29
Anti-parallel structure
One strand runs from five prime to three prime in the other runs from three prime to five prime
30
Meselson-Stahl Experiment
31
how many hydrogens bonds are between A and T
2
32
how many hydrogen bonds between G and C
3
33
meselson - Stahl experiment
put bacteria in nitrogen 15 and then 14 and then centrifuged it once to see if they were the same mass (semi + dispersive stayed) and then centrifuged it again for longer to see if the mass would change and semiconservative worked