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BACTERIOLOGY LECTURE > THE MYCOBACTERIUM > Flashcards

THE MYCOBACTERIUM Flashcards

(51 cards)

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1
Q

The general characteristics of Mycobacteria

A

Slender, slightly curved or straight rod-shaped organisms
Non motile
Non spore forming
Non-encapsulated
Strictly aerobic; catalase +

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2
Q

Mycobacteria produces what type of granules

A

Much granules

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3
Q

Acid responsible for its acid-fast staining characteristics

A

Mycolic acid

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4
Q

Consequences of high lipid content

A

Staining requires a longer time or application of heat
and once stained, it resist decolorization with acid-alcohol

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5
Q

The 3 major groups of Mycobacteria

A

Mycobacterium tuberculosis complex
Non-tuberculous mycobacteria (NTM)
Mycobacterium leprae

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6
Q

Organisms under the Mycobacterium tuberculosis complex

A

M. tuberculosis
M. bovis
M. africanum
M. microti
M. canetti

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7
Q

It is primarily a pathogen of the respiratory tract (TB)

A

Mycobacterium tuberculosis

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8
Q

It is once called “consumption”

A

Mycobacterium tuberculosis

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9
Q

Mycobacterium tuberculosis has a gram _________ cell wall

A

positive

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10
Q

M. tuberculosis has tapered ends and may exhibit “_______”

A

cording

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11
Q

It causes tuberculosis and Pott’s disease

A

M. tuberculosis

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12
Q

M. tuberculosis causes

A

tuberculosis and Pott’s disease

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13
Q

It is TB of the bone and muscles

A

Pott’s disease

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14
Q

Mycobacterium tuberculosis grows usually within …

A

8 weeks or 2 months

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15
Q

The virulent strains of Mycobacterium tuberculosis that is necessary to cause disease

A

Cord factor

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16
Q

The 3 types of tuberculosis

A

Primary TB
Secondary TB
Disseminated TB

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17
Q

A type of TB results from the initial infection of MTB

A

Primary TB

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18
Q

A type of TB results from the re-establishment of active infection after a period of dormancy

A

Secondary TB

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19
Q

A type of TB results when the infection spreads throughout the body

A

Disseminated TB

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20
Q

A macrophage in the lungs

A

Alveolar macrophage

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21
Q

A type of test that detects a patient’s cell-mediated immune response to bacterial antigen

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A

PPD (Purified Protein Derivative) Test

22
Q

It measures a person’s immune reactivity to specific mycobacterial antigens

Study These Flashcards
A

Interferon-Gamma Release Assays

23
Q

A zoonotic mycobacterium organism

Study These Flashcards
A

Mycobacterium bovis

24
Q

A zoonotic mycobacterium organism

Study These Flashcards
A

Mycobacterium bovis

25
Found primarily in cattle, dogs, cats, swine, parrots, and humans
Mycobacterium bovis
26
Has small, granular, rounded white colonies with irregular margins
Mycobacterium bovis
27
A mycobacterium organism that is slow grower, and non pigmented
Mycobacterium bovis
28
Primary agent of intestinal TB in man through ingestion of contaminated milk
Mycobacterium bovis
29
Mycobacterium bovis is a source of ...
BCG (Bacille Calmette-Guerin) vaccine
30
Atypical Mycobacteria is also known as ...
MOTT (Mycobacteria Other Than Tuberculosis) and NTM (Non-tubercle Bacillus)
31
It is an opportunistic pathogen in patients with liver disease, immunocompromised, percutaneous trauma
Atypical Mycobacteria
32
MOTT's classification
Runyoun's classification
33
Mycobacterium's classification is based on
Photoreactivity (ability to produce pigment)
34
The 4 groups in Runyoun's classification
GROUP1-Photochromogens GROUP2-Scotochromogens GROUP3-Nonphotochromogens GROUP4-Rapid growers
35
It produces carotene pigment upon exposure to light
GROUP1-Photochromogens
36
It produces carotene pigment in light or dark
GROUP2-Scotochromogens
37
No pigment; these colonies are a buff color
GROUP3-Nonphotochromogens
38
Non-pathogenic group which grows with in less than 7 weeks
GROUP4-Rapid growers
39
Organisms under GROUP1-Photochromogens
M. kansasii M. marinum M. simiae M. asiaticum
40
GROUP2-Scotochromogens
M. gordonae M. scrofulaceum M. flavescens
41
GROUP 3-Nonphotochromogens
M. avium M. gastri M. terrae M. xenopi M. ulcerans
42
GROUP 4-Rapid growers
M. fortiutum M. smegmatis M. phlei
43
It is also known as Yellow bacillus
Mycobacterium kansasii
44
Characteristics of Mycobacterium kansasii
Grows best at 37 degC Growth is evident in 14-28 days Tween 80 hydrolysis (positive) in 3 days Nitrate reduction (positive) Rapid Catalase Activity & Pyrazinamidase (negative) Causes Chronic Pulmonary Disease
45
Characteristics of Mycobacterium marinum
Grows optimally at 30-32 degC Growth at 24 degC and 32 degC occurs in 2 weeks Grows poorly or fails to grow at 35-37 degC Niacin Test (positive) Tween 80 (positive) Urease (positive) Pyrazinamidase (positive) Causes SWIMMING POOL GRANULOMA
46
Characteristics of Mycobacterium scrofulaceum
Causes CERVICAL LYMPHADENITIS Produces smooth, buttery, yellow to orange colo. in 4-6 weeks Pigment production evident in absence or presence of light Heat stable catalase (positive)
47
Characteristics of Mycobacterium szulgai
Photochromogen at 25 degC Schotochromogen at 35-37 degC Nitrate Reduction (positive) Tween 80 (slow positive) Fails to grow on 5% NaCl May cause pulmonary & cutaneous disease
48
Also known as Tap Water Bacillus
Mycobacterium gordonae
49
Characteristics of Mycobacterium gordonae
Usually non-pathogenic Previously known as M.aquae Grows in 7 days at 37 degC as yellow to orange colo. Tween 80 (positive) Heat stable catalase (positive)
50
Characteristics of Mycobacterium xenopi
Slow grower and produces small colonies Optimal growth at 42 degC On Cornmeal Agar produces branching colonies "Bird's Nest" Catalase (positive) Arylsulfatase test (positive) in 2 weeks Causes pulmonary infection in patients with pre-existing lung pathologies
51
It is a normal flora kind of mycobacterium
Mycobacterium flavescens

BACTERIOLOGY LECTURE (6 decks)

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