Thrombocytopenia Flashcards

1
Q

Differential diagnosis of Thrombocytopenia

A

-Increase platelet destruction or consumption :
○ITP
○TTP/HUS
○DIC
○Medications (e.g. heparin)
○SLE
○Antiphospholipid antibody syndrome

-Impaired production:
○Viral infection (EBV, HCV, HIV)
○Nutritional deficiency (B12 or folate deficiency)
○Bone marrow suppression or failure (chemotherapy, aplastic anemia, leukemia, myelodysplasia)
○Alcoholism

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