Thrombotic microangiopathy

Question 1

What is the relationship between MAHA and TMA?

Answer 1

Not all MAHA is caused by a TMA, but nearly all TMAs cause MAHA

Question 2

What does MAHA mean?

Answer 2

umbrella term for non-immune/coombs negative hemolysis (ie, Coombs-negative hemolysis) resulting from intravascular red blood cell fragmentation that produces schistocytes on the peripheral blood smear

Question 3

Drugs associated with drug induced TMA

Answer 3

tacrolimus
cyclosporine
sirolimus