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Flashcards in thyroid pathology Deck (26):
1

what do parafollcular cells ( C cells ) secrete?

calcitonin

2

what does cAMP do you levels of thyroid hormones?

increases them

3

what does this cause
? Hashimotos thyroiditis

hypthyroidism

4

what does this cause?
Graves?

hyperthyroidism

5

antibodies to TSH receptor?

graves

6

anti thyroglobulin antibodies and anti-peroxidase

hashimotos

7

any enlargement of thyroid

goitre

8

what stimulate gland enlargement?

low T3/4 levels cause a rise in TSH stimulating a growth in size

9

discrete solitary mass

encapsulated by a surrounding collagen cuff

composed of neoplastic thyroid follicles

can secrete thyroid hormones

thyroid adenoma

10

what are the 4 types of thryoid carcinoma?

papillary
follicular
medullary
anaplastic

11

most common thyroid cancer

papillary carcinoma

12

usually solitary nodule in thyroid which can be cystic of calcified

sometimes present with lymph node metastases

papillary carcinoma

13

second most common thyroid cancer

follicular carcinoma

14

usually a single nodule
slow enlarging
painless
rare lymphatic spread
but can spread by blood to bone lungs and liver

follicular carcinoma

15

what carcinoma is derived from C cells? and can secrete calcitonin

medullary carcinoma

16

what carcinoma is associated with amyloid deposition?

and is usallu aggressive

medullary carcinoma

17

undifferentiated and aggressive tumours
usually in older patients

rapid growth and involvement of neck structures and death

anaplastic carcinoma

18

thy 1

insufficient/cant interpret

19

thy2-

benign

20

thy3

probably benign

21

thy4

suspicious of malignancy

22

thy 5

malignant

23

how many glands are in a normal parathyrid?

4

24

what cells is the parathyroid composed of?

chief cells

25

what do chief cells secrete?

PTH

act on calcium homeostasis

26

what 2 things tend to cause hyperparathyroidism?

adenoma
hyperplasia