Flashcards in Topic 1 Deck (18):
any chemical substance that produces a biological effect
Uses of drugs (6)
- Therapeutic uses (for the treatment of diseases) [e.g. ibuprofen, fluoxetine]
- Experimental tools in biomedical research aimed at understanding physiological processes as well as elucidating the underlying causes of diseases in an effort to improve treatment. (to study the function of a cell or protein]. (e.g. PYR1, Phalloidin)
- Non-medical purposes -drugs that are used in the past for therapeutic purposes but are also used widely abused for non-medical purposes (e.g. amphetamines, cocaine and morphine)
- Drugs used in a social (or anti-social) context (e.g. nicotine).
- Toxic - to produce a deleterious effect (e.g. apamin, strychnine)
- Nefarious (wicked/criminal)
What draws all the diverse types of substances under the title of drugs
that they produce effects in the body
drugs that are used specifically for a therapeutic purpose
Can medicines be poisons/ can poisons be medicines
Medicines can be poisons (at high doses) and poisons can be medicines
When drugs are used as medicines, why they are usually combined or formulated with other substances
to be easily administered and more readily tolerated. The additional substances are used to provide stability of the active drug or two improve the taste if the drug is to be taken by mouth.
a substance that produces a harmful or toxic effect in the body.
At high enough levels, all drugs may produce
What is often the difference between a drug and poison
Often, the difference between a drug and a poison is determined by the dose taken
Examples of poisons
workplace chemicals; environmental pollutants; and naturally occurring compounds such as animal venoms or plant poisons.
Similarities of pharmacology and toxicology
both look at drugs
a branch of science concerned with the study of drugs and medicines. This includes their discovery, development/manufacture, effects, side effects and fate in the body, as well as uses. The study of drugs and their interactions with living systems.
Pharmacology comes from the Ancient Greek word...
discipline that is concerned with the preparation and dispersing of drugs
Divisions of pharmacology
the study of the fate of drugs and medicines in the body (what does the body do to drugs, how is it taken, how does the body clear it)
the study of the actions of drugs and medicines in the body (what do drugs and medicines do in the body and how do they achieve their effects in the body) [where it acts, what the effects are]