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Flashcards in Topic 1 Deck (10):
1

The basic concepts of Pharmacology that emerged from early studies are (4)

- medicinal extracts obtained from natural sources contain specific compounds or pharmacologically active agents responsible for their effects. Many of these agents or their derivatives including alkaloids, glycosides, hydrocarbons, steroids and oils are currently used or have been used as drugs, medicines and poisons
- drugs produce their effects by interacting with specific molecular targets in the body
- the effects of drugs are determined by their chemical - structures and alterations of the structure of a drug are likely to affect its action
- there is a definite relationship between the amount or dose of a drug and its effect.

2

Types of drug names (3)

- Chemical name (e.g. acetylsalicylic acid)
- Generic name (e.g. aspirin)
- Trade (proprietary) name (e..g Aspro®)

3

Chemical name

describes the chemical nature of the drug

4

Generic name

the approved name, assignment by the manufacturer by which the drug is officially known

5

Trade (proprietary) name

the name assignment for marketing by the manufacturers. A drug may have more than one trade name if its manufactured by different companies. [For drugs that are marketed for use in medicine]

6

All drugs have at least how many names and what are they

two names (chemical name and generic name)

7

Drugs may be classified in a number of ways including (5)

1) source (e.g. salicylic acid (from the botanical name for the Willow family, Salicaceae)
2) chemical structure (e.g. salicylic acid derivatives)
3) therapeutic use (e.g. anti-inflammatory)
4) mechanism of action (e.g. cyclooxyrgenase inhibitor - explains how the drug works)
5) prototype drug (e.g. aspirin like)

8

Sources of drug information

Official reference texts include pharmacopoeias and formularies. Other sources include drug bulletins and updates (usually produced by government bodies and refer to specific drugs); MIMS annual and reference textbooks.

9

Pharmacopoeias

provides information relevant to particular countries about the drug formulas, strengths and dosage.

10

Formularies

contains information about drug actions, side effects and guidelines for pharmacists