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Flashcards in Topic 2 Deck (26):
1

What considerations must be taken when administering medication (5)

1) diseases/symptoms are suavely localised to a site (e.g. receptor, cell or organ); 2) drugs must get to this site of action; 3) must get there at an effective dose to treat the symptom; 4) timeframe of action should be appropriate; 5) method of delivery should be convenient for the person being treated.

2

What do medicines aim to do

medicines work to either treat a symptom (e.g. relieve a stuffy nose) or fix a problem (e.g. a bacterial infection)

3

Route of drug administration

the way in which it enters the body

4

The route of drug administration is an important factor influencing what

whether the drug reaches its site of action and if so, how quickly and how much of it gets there

5

List of the most common routes of administration (8) SOOIIITS

- Oral (swallowing a tablet or syrup)
- Sublingual (dissolving a tablet under the tongue)
- Inhalation (through the respiratory passage) [e.g. puffer]
- Intramuscular (getting an injection in an arm, leg or other muscle)
- Subcutaneous (an injection just under the skin)
- Intravenous (an injection into a vein)
- Transdermal (wearing a skin patch or applying a skin cream)
= Other (e.g. suppositories, eye drops)

6

Example of oral administration

aspirin tablet

7

Advantages of oral administration

easy for patient, convenient and effective

8

Disadvantages for oral administration

drug may be broken down in GI tract before reaches target

9

Example of sublingual administration

glyceryl trinitrate

10

Advantages of sublingual administration

rapid onset of action

11

Disadvantages of sublingual administration

unsuitable for many drugs due to properties

12

Example of inhalation

salbutamol

13

Advantages of inhalation

gets directly to site of action

14

Disadvantages of inhalation

requires practice to use

15

Example of intramuscular administration

tetanus vaccine

16

Advantages of intramuscular administration

muscles have good supply of blood vessels

17

Disadvantages of intramuscular administration

soreness at site of injection

18

Example of subcutaneous administration

insulin

19

Advantages of subcutaneous administration

can be self-administered

20

Disadvantages of subcutaneous administration

some people don't like needles

21

Example of intravenous administration

morphine drip

22

Advantages of intravenous administration

rapid onset, sustained action, ensures all drug enters the blood stream

23

Disadvantages of intravenous administration

dosage must be carefully monitored

24

Example of transdermal administration

nicotine replacement therapy patches

25

Advantages of transdermal administration

can be slow release

26

Disadvantages of transdermal administration

drugs may not absorb well through skin