Toxicology Flashcards

(72 cards)

0
Q

This herbicide attacts lung surfactant thus causing ARDS

A

Glycine. (glyphosate)

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1
Q

Most widely used herbicide in the world

A

Glycine

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2
Q

Herbicide known to cause true HL.

A

PCBs

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3
Q

Withe ndocrine disruptors, what type of cancer is associated with them?

A

BREAST and other reproductive cancers

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4
Q

This class of environmental pollutants are known to cause mimic enhance or inhibit a hormonal action.

A

Endocrine disruptors.

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5
Q

Phytoestrogens and mycoestrogens are classified as?

A

Endocrine disruptors.

Phytoestrogens- anti androgenic
Mycoestrogens

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6
Q

Give the three metalloids.

A

ABC

Asbestos
Berryllium
Cadmium

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7
Q

This herbicide is also known to cause YUSHO disease in Japan.

A

PCBs. Polychlorinated Biphenyls

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8
Q

This metalloid is known to cause chronic pulmonary fibrosis as an autoimmune attack on the skin and lungs

A

Berryllium

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9
Q

This metalloid most commonly causes lung cancer

A

Asbestos

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10
Q

This metalloid may also cause nephroblastom or renal failure

A

Cadmium

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11
Q

Name three heavy metals.

A

LAM

lead
Arsenic
Mercury

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12
Q

Oldest heavy metal occupational and environmental poison.

A

Lead

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13
Q

Give the route,

Industrial LEAD poisoning
Non-industrial LEAD poisoning

A

Industrial - respi

Non-industri - gastro

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14
Q

This type of lead is mainly found on paints, foods, drinks and industrial fumes

A

Inorganic lead

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15
Q

This lead is commonly used before as an antiknock additive in gasoline

A

Inorganic lead

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16
Q

Can be universally given if one does not know the name of poison as an antidote

A

IM DIMERCAPROL

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17
Q

This causes oliguric renal failure, hence hemoglobinuria

A

Organic arsenic

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18
Q

Used as an intravenous drug for inorganic lead poisoning

A

Calcium disodium edetate

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19
Q

This mettalloid mainly causes pneumonia or fibrosis in WELDERS.

A

Cadmium

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20
Q

Oral derivative of succinic acid used as antidote for inorganic lead poisoning

A

Succimer

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21
Q

Between types of arsenic, which cannot be treated with chelation

A

Organic arsenic.

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22
Q

Type of arsenic wherein which hemodialysis is the ultimate treatment

A

Organic arsenic

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23
Q

Aside from lead, this heavy metal can pr esent with basophilic stippling

A

Inorganic arsenic

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24
Inorganic can be treated with UNITHIOL and DIMERCAPRIOL but ni oral form is available. T or F
True
25
Between the types of lead, skin exposure is poorly absorbed
Inorganic,
26
This heavy metal presents with raindrop hyperpigmentation of the skin
Inorganic arsenic
27
Give the triad for chronic mercury poisoning
NTG neuropsych disturbances tremor gingivostomatitis
28
Erethism and acrodynia are common in what heavy metal poisoning.
Mercury
29
Give the route of mercury absorption of the following types: Elemental - Organic - Inorganic -
Inhalation Inhalation, Ingestion Percutaneous
30
Universal antidote
Dimercaprol
31
What heavy metal presents with ALDRICH-MEES lines?
Inorganic arsenic
32
Used in iron overdose, oral form
Deferasirox
33
What element is missing for patients with PD
Manganese. Give edta
34
Used as iron chelator, intravenous form
Deferoxamine
35
Used in cesium and thalium
Prussian blue
36
Used for Wilson's disease
Penicillamine
37
Can be given for patients with Klinefelter rings
Penicillamine
38
These are drugs that reverse the toxic effects of heavy metals or drugs by accelerating elimination.
Chelators
39
For patients with megaloblastic anemia, what elements can be given
Co. B12
40
What can be given in cases of cyanide poisoning.
Vit c. Converts cyanomethemoglobin to normal hemoglobin
41
This element requires triple antidote consisting of vitamin c, b12 and nano2 or nas2so4
Cyanide
42
Characterized as having bitter almond breathe. And can be due tomescessive cassava ingestion
Cyanide
43
Can lavage be done to patient who ingested petroleum?
No. Corrosive
44
Give drugs who are dopamine agonist
AN ACE
45
Give drugs that are G protein coupled
Opiods Cannabis mescaline GBH
46
Drugs that are ionitropic
Ketamine Bdz Alcohol Nictotine
47
Drugs that are transporter of biogenic amines
ACE amph Cocaine Ecatacy
48
Alcohol dehydrogenase inhibitor
Fomepizole
49
Avetalfehyde dehydrogenase inhibitor
Disulfiram
50
For rehab treatment on alcoholism
Naltrexone
51
GABA agonist but NMDA antagonist
Acamprosate
52
Can be given to rekax muscles
Baclofen
53
Given for delirium tremens
Topimarate
54
Given in cessation of cigarette smoking but was then banned because of obesity
Rimonabant
55
Commonly abused substance by health prof
Meperidine
56
Causes visual disturbance as snow storm
Methanol
57
Used as an antifreeze. Vision is normal
Ethylene glycol
58
Characterized as with fomaldehyde breath
Methanol
59
DOC for both methanol and ethylene
Ethanol
60
Also known as ma huang
Meth
61
True or false. Both methylene and ethylene cause met acidosis
True
62
Heroine is characterized with nasal perforation.
True
63
This drug is characterized as having blood shot eyes.
Marijuana
64
This drug causes an increase in apetite
Marijuana
65
Give the blood alcohol level and their clinical effects.
SAECD ``` 50-100 --- sedation 100-200 ---- ataxia 200-300 ---- emesis, stupor 300-400 ---- coma >500 --- death ```
66
When does delirium tremens appeaR?
After 3-4 days of alcohol withdrawal.
67
What subs causes pulmo fibrosis
PBB Paraquat, bleomycin, busulfan
68
What cause hepatic necrosis
Acetaminophen, 14tabs plus | Mushroom
69
Drug for watusi
Acetaminophen Phytonadione Cal gluc
70
Acute alcohol overdoze
Naloxone
71
BDZ antidote
Flumazenil