translation 2- post translational modification and exp

Question 1

proteolytic cleavage

Answer 1

digestive enzyme: trypsinogen to trypsin
CF:prthrombin to thrombin
h: proinsulin to insulin+c-peptide

Question 2

disulphide bond formation

Answer 2

secreted proteins

Question 3

att of prosthetic grp

Answer 3

covalent linkage of biotin to carboxylates

Question 4

glycosylation ( serione,threonine,asparagine)

Answer 4

membrane and secreted proteins
- ABO blood grp determinants
-Ig

Question 5

phosphorylation ( s,3,ty)

Answer 5

glycogan synthase,pyruvate kinase
-hormonally regulated enzymes

Question 6

hydroxylation (lysine and proline)

Answer 6

collagen alpha chains

Question 7

gamma-carboxylation (glutamine)

Answer 7

CF: 2,7,9,10.protein C and S