transmission between neurons

Question 1

synaptic transmission

Answer 1

AP
Ca channel opens
Ca2+ enters vesicles and fuse with membrane
pore opens
release of NT
NT diffuses
binds to postsynaptic membrane
postsynaptic channels open
ion flow

Question 2

binding

Answer 2

neurotransmitter binds to binding site on postsynaptic membrane
postsynaptic potential depends on which ion channel is open

Question 3

receptors

Answer 3

ionotropic
- contains binding site and ion channel
- opens when molecule attaches to site
metabotropic
- contains binding site
- chain reaction opens ion channels
- requires energy
- slower than ionotropic

Question 4

termination

Answer 4

reuptake:
transmitter taken up presynaptic terminal via transporter molecule
enzymatic deactivation:
- transmitter broken down by enzyme

Question 5

neural integration

Answer 5

excitatory - increase likelihood of neuron firing
inhibitory - decrease likelihood of neuron firing
integration - summation of PSPs in control of firing

Question 6

GABA

Answer 6

• learning neurotransmitter
• facilitate neural signalling across cortex
• most abundant in cells
• main inhibitory in brain

Question 7

acetycholine

Answer 7

• small molecule
• intentions to actions
• signal from neuron to muscle fibre
• both excitatory and inhibitory

Question 8

dopamine

Answer 8

• pleasure chemical
• released when rewarded
• motor control
• neuromodulator

Question 9

glutamate

Answer 9

• excitatory
• death of neurons
• learning and memory

Question 10

serotonin

Answer 10

• calming chemical
• mood modulating
• manage appetite, sleep, memory, decision making
• excitatory and inhibitory

Question 11

drugs and neurotransmitters

Answer 11

antagonist - blocks neurotransmitter
agonist - mimic neurotransmitter and enhances synaptic function