Treating Cardiovascular Disease Flashcards Preview

Pharmacology > Treating Cardiovascular Disease > Flashcards

Flashcards in Treating Cardiovascular Disease Deck (13):
0

What can CVD lead to?

Heart attacks, stroke and gangrene

1

What life styles factors is CVD accentuated by?

Obesity, diabetes and type 2 diabetes

2

What is atherosclerosis?

The build up of fatty acids in the arteries which form plaques. The plaques become unstable and fragmentation occurs which causes clotting which eventually clots the artery.

3

What is hypertension?

High blood pressure

4

What is very powerful in protecting against CVD?

Exercise

5

What system controls blood flow?

The renin angiotensin system

6

What does angiotensin converting enzymes convert?

Angiotensin one to two

7

What drug inhibits angiotensin converting enzyme and why?

Captopril, do cause dilation and lowers blood pressure

8

What is candersartan?

An antagonist for the AT1 receptors and stops angiotensin 2 binding used to treat hypertension

9

What is used to treat type 2 diabetes?

Metformin

10

What is dyslipidaemia?

A problem with lipids - 'the emergence of lipid lowering'

11

How is dyslipidaemia treated?

With simvastatin which inhibits HMG CoA reductase

12

What is used to treat atherothrombosis?

Aspirin, it inhibits the anti-aggregatory action of PGI2, and clopidogrel, which is an antagonist for purine 2Y receptor, are taken in combination