Flashcards in Treating Cardiovascular Disease Deck (13):
What can CVD lead to?
Heart attacks, stroke and gangrene
What life styles factors is CVD accentuated by?
Obesity, diabetes and type 2 diabetes
What is atherosclerosis?
The build up of fatty acids in the arteries which form plaques. The plaques become unstable and fragmentation occurs which causes clotting which eventually clots the artery.
What is hypertension?
High blood pressure
What is very powerful in protecting against CVD?
What system controls blood flow?
The renin angiotensin system
What does angiotensin converting enzymes convert?
Angiotensin one to two
What drug inhibits angiotensin converting enzyme and why?
Captopril, do cause dilation and lowers blood pressure
What is candersartan?
An antagonist for the AT1 receptors and stops angiotensin 2 binding used to treat hypertension
What is used to treat type 2 diabetes?
What is dyslipidaemia?
A problem with lipids - 'the emergence of lipid lowering'
How is dyslipidaemia treated?
With simvastatin which inhibits HMG CoA reductase