Treatment and Control of Bacterial and Fungal Infections Flashcards Preview

Bacteriology Exam 1 > Treatment and Control of Bacterial and Fungal Infections > Flashcards

Flashcards in Treatment and Control of Bacterial and Fungal Infections Deck (26):
1

Compounds that disinfect living tissue

Antiseptics

2

Compounds that disinfect non-living surfaces

Disinfectants

3

What is the single most important infection control measure?

Hand hygiene

4

Validated process used to render a product free of all forms of microorganisms, including all bacterial endospores

Sterilization

5

Elimination of most if not all pathogenic microorganisms EXCLUDING spores

Disinfection

6

Reduction of pathogenic mocroorganisms to a level where items are "safe to handle" without protective attire

Decontamination

7

Drugs that destroy microbes, prevent their multiplication or growth, or prevent their pathogenic effect

Antimicrobials

8

Substance produced by a microorganism that inhibits or kills other microorganisms

Antibiotic

9

Any substance of synthetic, semisynthetic, or synthetic origin that inhibits the growth of microorganisms but causes little or no damage to the host

Antimicrobial

10

All _____ are ______, but not all _____ are _____

Antibiotic, antimicrobial, antimicrobial, antibiotc

11

How are antimicrobials classified?

Mode of action

12

Antibacterials active against both Gram-positive and Gram-negative organisms

Broad spectrum

13

Antibacterials with limited activity and are primarily only useful against particular species of microorganisms

Narrow spectrum

14

Type of antimicrobial activity that kills bacteria

Bactericidal

15

Type of antimicrobial activity that inhibits bacterial growth

Bacteriostatic

16

What are the two types of Antimicrobial Susceptibility Testing?

Disk diffusion test and broth/agar dilution test

17

Minimum amount of drug required to inhibit bacterial growth

Minimum inhibitory concentration (MIC)

18

Drug concentration above which an organism is considered resistant and at or below this value organism is susceptible to that drug

Susceptibility break point

19

What are the three susceptible break point values?

Susceptible, intermediate, resistant

20

Must use a bacterial isolate in pure culture for this AST

Disk diffusion test

21

Which AST uses both diffusion and dilution

Gradient diffusion test, E-test

22

Susceptibility results interpret...

Likelihood of therapeutic success/failure, uncertain therapeutic outcome

23

Fate of the drug in the body (absorption, transformation, distribution, elimination)

Pharmokinetics

24

Effect of the drug on the body, mechanism of action and efficacy

Pharmacodynamics

25

Preexisting genomic property contributes to _____ resistance

Innate

26

_____ resistance is acquired by mutation or horizontal gene transfer

Acquired