Tularemia Flashcards
(25 cards)
Most virulent sps of tularemia ? Region and mortality
North America
A and 5-5%
Talk about tyoe B
Mortality less than 5% and it causes tularemia in Europe and asia
List the forms of tularemia
Ulceroglandular
Glandular
Typhoidal
Pneumonic
Septic
Oculoglandular
Oropharyngeal
List the routes if transmissions
Skin - handling infected animals
GIT coining contaminated meat poorly
Resp tract. Aerosol inhalation
Skin- bite of blood sucking deer flies and wood ticks
What hemisphere is tuleremia highly prevalent
The northern
They form spores
They do not
Found in where
Soul water moist hay straw decaying animal carcasses
Considering the reservoirs
What size are the natural reservoirs
Small and medium sized
Rabbits
Rats
Muskrats
Squirrels
Lemmings
Mice
List some vectors
Ticks
Mosquitos
Biting flies
Which mosquito transmits tuleremia
Culex mosquitos
Francisella tularemia is a _____ staining … ______gram ______
Weakly staining
Negative
Coccibacilli
Size
0.2-0.7 nm
Considering the morphology of the organism is it motile or not
Not
what stain ?
Giemsa stain
Bipolar staining
Catalase positive or negative
Positive
Young cultures are ______ in appearance and older cultures show ________
Uniform … pleomorphism
Carbs are disssimilated______ with the ________
Slowly with the production of acid but no gas
Has a capsule.. describe
It has a thick capsule and it is responsible for the virulence
Lipid conc in the capsule and cell wall values
50:70
Regarding culture characteristics
1. Optimal growth and growth range
2. _____ growing with requirement _____
37
24-39
Slow growing
Iron and cysteine
What about hemolysis
No true hemolysis just greenish discoloration
Treatment of tularemia
Tetracyclines and chloramphenicol
WHich detection method is more accurate and sensitive
TRF is more accurate than ELISA
List other detection systems
Mass spectrometry
TRF
ELISA
PCR
