Tumor Markers Flashcards Preview

Unit 1: Neoplasia > Tumor Markers > Flashcards

Flashcards in Tumor Markers Deck (32):
0

PSA

Prostate

1

CEA

Colon and other GI

2

CA125

Ovaries

3

HER2/neu

Breast

4

CD20

B-cell lymphoma

5

C-kit

GI stromal

6

EGFR

Lung and colon cancer

7

Cytokeratins

Carcinomas

8

Thyroglobulin

Thyroid

9

Lewis a antigen (CA 19-9)

Pancreas and GI

10

Estrogen and progesterone

Breast

11

Chromogranins

Neuroendocrine

12

Synaptophysin

Neuroendocrine

13

Leu-7 (CD57)

Neuroendocrine

14

CK20

Colon

15

HMB-45 and S-100

Melanoma

16

Vimentin

Soft tissue sarcoma

17

Desmin

Smooth or striated muscle

18

Muscle-specific actin

Muscle

19

Neurofilament proteins

Neurons (ex. neuroblastoma and ganglioneuroma)

20

GFAP, Glial Fibrillary Acidic Protein

Astrocytes, other glial cells

21

LCA (CD45)

Leukocyte common antigen - malignant lymphoma

22

Factor VIII related antigen

Vascular tumors (ex. hemangioma, hemangiosarcoma)

23

AFP

Liver or non-seminomatous germ cell (yolk sac) tumors

24

PCNA

Proliferating cell nuclear antigen - cell proliferation

25

PLAP, placental alkaline phosphatase

Seminoma or embryonal carcinoma (testis or ovary)

26

hCG

Trophoblastic tumors, ex. choriocarcinoma (placenta)

27

Calcitonin

Thyroid

28

Bcl-1 and cycling D1

Mantle cell lymphoma

29

Pigmented metastases

Malignant melanoma

31

CD4

T cells

32

Ki-67

cell proliferation