Tumor Markers Flashcards

1
Q

CEA

A

Carcinoembryonic antigen (non-specific; produced by about 70% of colorectal and pancreatic cancers; also produced by gastric, breast, and thyroid medullary carcinomas)

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2
Q

a-fetoprotein

A

Hepatocellular carcinomas

Nonseminomatous germ cell tumor of testis (i.e. yolk sac tumor)

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3
Q

b-HCG

A

H - hydatidiform moles
C - choriocarcinomas
G - Gestational trophoblastic tumors

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4
Q

CA-125

A

Ovarian, malignant epithelial tumors

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5
Q

S-100

A

Melanoma, neural tumors, schwannomas

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6
Q

Alkaline phosphatase

A

Metastases to bone, obstructive biliary disease, Paget’s disease of bone

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7
Q

Bombesin

A

Neuroblastoma, lung/gastric cancer

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8
Q

TRAP (tartrate-resistant acid phosphatase)

A

Hairy cell leukemia (a Bcell neoplasm)

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9
Q

CA-19-9

A

Pancreatic adenocarcinoma

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10
Q

Calcitonin

A

Thyroid medullary carcinoma

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