Flashcards in Tumor Markers Part 2 Deck (18):
this tumor marker is seen in primary or secondary liver cancer; greatest elevation seen in patients with prostate cancer with bone metastases
This tumor marker can detect non-Hodgkin's lymphoma, acute leukemia, and testicular cancer.
This tumor marker is found in neuronal tissue and detects neuroblastomas, carcinoid tumors, and pheochromocytoma.
Neuron-Specific Enolase (NSE)
This tumor marker is primarily used to screen, stage, and monior treatment and recurrence of prostate cancer.
Prostate specific antigen (PSA)
This tumor marker detects pituitary tumors or ectopic ACTH producing tumors
adrenocorticotrophic hormone (ACTH)
This tumor marker is used to detect familial medullary carcinoma of the thyroid (autosomal dominant)
This tumor marker is used to detect gastrinomas, which cause Zollinger-Ellison syndrome
This marker is elevated in trophoblastic diseases (associated with the uterine endometrial lining) and germ cell tumors; can go along with AFP to identify testicular tumors
Human Chorionic Gonadotropin
these two catecholamines are increased in pheochromocytomas (tumors in adrenal medulla)
epinephrine and norepinephrine
This catecholamine is increased in neuroblastomas
This tumor marker arises from carcinoid tumors of the GI tract and pancreas
serotonin and 5-HIAA
In cancer patients, production of these antigens demonstrates that certain genes are reactivated during malignant cellular transformation.
this is found in hepatocellular and germ cell (non-seminoma) carcinoma
this marker is useful for colorectal carcinoma (70%) COLON CANCER
carcinoembryonic antigen (CEA)
This marker is elevated in 69% of cases of breast cancer; not used to diagnost but most useful in followup of treated breast cancer
This marker is used for the detection of recurrent breast cancer in patients with stage II or stage III disease
This marker is usedful in detecting active breast cancer, but not early breast cancer