Tumor Markers Part 2 Flashcards Preview

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Flashcards in Tumor Markers Part 2 Deck (18):
0

this tumor marker is seen in primary or secondary liver cancer; greatest elevation seen in patients with prostate cancer with bone metastases

ALP

1

This tumor marker can detect non-Hodgkin's lymphoma, acute leukemia, and testicular cancer.

LD

2

This tumor marker is found in neuronal tissue and detects neuroblastomas, carcinoid tumors, and pheochromocytoma.

Neuron-Specific Enolase (NSE)

3

This tumor marker is primarily used to screen, stage, and monior treatment and recurrence of prostate cancer.

Prostate specific antigen (PSA)

4

This tumor marker detects pituitary tumors or ectopic ACTH producing tumors

adrenocorticotrophic hormone (ACTH)

5

This tumor marker is used to detect familial medullary carcinoma of the thyroid (autosomal dominant)

calcitonin

6

This tumor marker is used to detect gastrinomas, which cause Zollinger-Ellison syndrome

Gastrin

7

This marker is elevated in trophoblastic diseases (associated with the uterine endometrial lining) and germ cell tumors; can go along with AFP to identify testicular tumors

Human Chorionic Gonadotropin

8

these two catecholamines are increased in pheochromocytomas (tumors in adrenal medulla)

epinephrine and norepinephrine

9

This catecholamine is increased in neuroblastomas

dopamine

10

This tumor marker arises from carcinoid tumors of the GI tract and pancreas

serotonin and 5-HIAA

11

In cancer patients, production of these antigens demonstrates that certain genes are reactivated during malignant cellular transformation.

oncofetal antigens

12

this is found in hepatocellular and germ cell (non-seminoma) carcinoma
LIVER CANCER

alpha fetoprotein

13

this marker is useful for colorectal carcinoma (70%) COLON CANCER

carcinoembryonic antigen (CEA)

14

This marker is elevated in 69% of cases of breast cancer; not used to diagnost but most useful in followup of treated breast cancer

CA 15-3

15

This marker is used for the detection of recurrent breast cancer in patients with stage II or stage III disease

CA 27.29

16

This marker is usedful in detecting active breast cancer, but not early breast cancer

CA 549

17

This is used as a marker for ovarian cancer, useful in differentiating benign from malignant disease in patients with palpable ovarian masses

CA 125