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Flashcards in Tumor of bone and skin Deck (12):
1

Soap bubble appearance on Xray

Giant cell tumor

2

Benign tumors of bone:

Giant cell tumor (20-40; epiphyseal end) and Osteochondroma

3

Most common benign tumor

osteochondroma
rarely transforms to chondrosarcoma

4

Malignant tumors

Osteosarcoma (10-20 years old) and Ewing Sarcoma (boys <15 years old)

5

Ewing sarcoma:

onion skin appearance and 11;22 translocation

6

Osteosarcoma

most common malignant tumor; codman triangle; sunburst appearance

7

Common mets to the bone:

Prostate, renal, thyroid/testes, lung, breast
"Permanantely relocated tumors like bones"

8

What primary tumor causes blastic lesions in bone?

prostate

9

What causes achondroplasia

FGFR3

10

Cystic bone spaces filled with brown fibrous tissue

Osteitis fibrosa cystica

11

Tx for osteoporosis:

stop smoking, stop alcohol consumption, stop steroids, avoid PPIs and H2 blockers, exercise, vitamin D and Ca supplementation, bisphosphonates, terparatide

12

Other txs for osteoporosis:

conjugated estrogen, SERM (raloxifene),calcitonin, Denosumab (RANKL inhibitor)