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Flashcards in Tumors Rumors and Bad Humors Deck (87)
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1
Q

Where do angiosarcoma originate in heart most often?

A

Right Atrium

2
Q

Where do fibroma originate in heart most often?

A

LV

3
Q

Where do mesothelioma tumors originate in heart most often?

A

Pericardium

4
Q

Where do rhabdomyoma tumors originate in heart most often?

A

RV = LV

5
Q

Where do papillary fibroelastoma originate in heart most often?

A

Mitral Valve

Aortic Valve

6
Q

Rhabdomyoma are associated with what disease?

A

Tuberous Sclerosis

7
Q

Where is the most common place to find a myxoma?

A

Left Atrium

8
Q

What is the most common malignant tumor of the heart?

A

Metastatic

9
Q

What is the most common cardiac neoplasm in adults?

A

Myxoma

10
Q

What is the most common sarcoma tumor of the heart?

A

Angiosarcoma

11
Q

What is the most common metastatic cancer that has cardiac involvement?

A

Melanoma

12
Q

What is the most common tumor found in the vena cava?

A

Renal Cell Carcinoma

13
Q

What % of Primary Cardiac Tumors are benign?

A

75%

14
Q

What % of Primary Cardiac Tumors are malignant?

A

25%

15
Q

What is the most common primary cardiac benign tumors?

A

Myxoma

16
Q

Other than sarcomas, what is the 2nd most common malignant cardiac tumors?

A

Lymphomas

17
Q

What is the typical age group of myxoma?

A

30 - 60 year olds (Middle aged)

18
Q

What is the typical gender where myxoma are found?

A

Women > Men

19
Q

What is the location where myxomas are commonly found?

A
  1. LA (75%)
  2. RA (23%)
  3. LV/RV (2%)
20
Q

Where are the myxomas commonly attached in the atriums (Left > Right)

A

Fossa Ovalis

Depression in the right atrium of the heart, at the level of the interatrial septum, the wall between right and left atrium. The fossa ovalis is the remnant of a thin fibrous sheet that covered the foramen ovale during fetal development.

21
Q

What are myxomas characterized as?

A

Protruding “fronds” of tissue or “Grape cluster” appearance

Frond: the leaf or leaflike part of a palm, fern, or similar plant

22
Q

Ventricular Myxoma:

More common in what population?

A

Women and Children (Multiple/Familial)

23
Q

Where are lipomas found in the heart (usually)?

A

Extramyocardial

Subpericardial

24
Q

What is lipomatous Hypertrophy?

A

Lipomatous hypertrophy of the interatrial septum (LHIS) is a relatively uncommon disorder of the heart characterized by benign fatty infiltration of the interatrial septum.

It is commonly found in elderly and obese patients as an asymptomatic incidentally discovered finding.

25
Q

Where are fibroelastomas traditionally seen?

A

Downstream side of valve (LV side of MV or Aorta side of AV)

26
Q

What are the echo characteristics of fibroelastomas?

A

Well demarcated homogenous texture

Small

Mobile stalk

Single vs. Multiple

27
Q

What are the two most common types of primary malignant cardiac tumors?

A
  1. Sarcoma (95%)
  2. Lymphoma (5%)
28
Q

What are the two most common type of sarcomas found in the heart?

A
  1. Angiosarcoma
  2. Rhabdomyosarcoma
29
Q

What populaton is angiosarcomas most common?

A

Middle aged men

30
Q

Where are angiosarcomas most common found?

A

RA

31
Q

What is the most common cardiac malignancy in pediatrics?

A

Rhabdomyosarcoma

32
Q

Where are rhabdomyosarcomas found?

A

Ventricular Wall

33
Q

Which is more common, primary or secondary cardiac tumors?

A

Seconary > 20x more common

34
Q

What is the most common primary source of secondary cardiac tumors?

A
  1. Lung
  2. Breast
  3. Melanoma
  4. Leukemia
  5. Lymphoma
35
Q

In malignant melanoma, what % of these patients have tumors in the heart?

A

50%

36
Q

What is seen here in the image?

A

“Charcoal” view of the heart where tumor is on the pericardial space

37
Q

Answer the question

A

Carcinoid Heart Disease

  • Funnel shaped leaflets don’t open or close well
38
Q

What is the most common cause of acquired pulmonic stenosis is what?

A

Carcinoid Heart Disease

39
Q

What % of carcinoid patients will develop carcinoid heart disease?

A

>50%

40
Q

Where do carcinoid heart disease patients usually have metastatic disease?

A

Hepatic Mets (Large amounts of serotonin) Reach right heart before inactivated by monoamine oxidases in the lungs

41
Q

What happens to the leaftlets in carcinoid heart disease?

A

Leaflets appear thickened and shortened

(Progression they become retracted and hypomobile)

42
Q

What is found in Carcinoid Heart Disease on the TV?

A

Early peak velocity nad steep decline

“Dagger” Shaped profile

43
Q

What is seen before the left atrial appendange here?

A

Left Atrial Appendage Membrane

44
Q

Which is more common in Carcinoid Heart disease:

TS or PS?

A

PS > TS

(Tricuspid valve has a huge annulus and much bigger than pulmonic valve

45
Q

What would be an indication for surgery of a patient with pulmonic stenosis?

A

PS Gradient > 10 mmHg

46
Q

PR is present in what percent of patients with a normal pulmonic valve in presence of carcinoid heart disease?

A

40-78%

47
Q

What 3 scenarios would is be feasible to have left sided cardiaac involvement from carcinoid disease?

A
  1. PFO (Intracardiac shunts)
  2. Extensive primary bronchial carcinoid
  3. High tumor secretions or poorly controlled disease overwhelming capactiy of the lungs (Overcomes the mono-amine oxidase ability)
48
Q

In a patient with carcinoid right sided heart disease, is a balloon valvuloplasty recommended?

A

No because of TR and PR

49
Q

What are the 2 considerations in mechanical and bioprosthetic valve replacements for carcinoid disease

A

Mechanical

  1. Less degeneration from carcinoid plaques
  2. Higher Thrombotic risk

Bioprosthetic

  1. More degeneration from carcinoid plaques
  2. Lower Thrombotic risk
50
Q

What cardiac conditions are associated with Epstein anomalies?

A
  1. Intracardiac Shunts (secundum ASD)
  2. WPW (Tachyarrythmias)
51
Q

Epstein Anomaly:

What is malformed?

A

TV and RV

52
Q

Epstein Anomaly:

What is the cause?

A

Failure of delamination (splitting of tissue by attachment of inner layer during embryological development)

53
Q

What two leaflets are involved in Epstein anomaly?

What do they look like?

A

Septal and Anterior

Septal = Apically displaced

Anterior = Redundant with fenestrations “Sail” extending into the RV

54
Q

Comment on the mitral valve insertion in Ebstein Anomaly?

A

Anterior Leaflet = Located More towards base of the heart (Compared with the septal leaflet of the tricuspid valve)

55
Q

What is the diagnostic value for Ebstein anomaly?

A

>8 mm/m2 BSA of the insertion of the septal leaflet from the insetion point on the mitral valve leaflet

56
Q

What can happen to the LV in Ebstein Anomaly?

A

LV Non-compaction

phenotype of hypertrophic ventricular trabeculations and deep interventricular recesses. It has been hypothesized to result from arrest of normal myocardial compaction during embryogenesis

57
Q

What is this?

A

Cor triatriatum dexter is a rare congenital heart anomaly where the right atrium is divided into two chambers by a membrane.

58
Q

Cor triatriatum dexter is caused from what?

A

Failure of resorption of common pulmonary veins during embryogenesis

59
Q

Which is more common:

Cor triatriatum dexter or Cor triatriatum sinister?

A

Sister (left sided) = More common

60
Q

If you find Cor triatriatum dexter, what are the salient points that you need to keep in mind to look for on echo?

A
  1. Flow Obstruction presence using doppler?
  2. Evaluate Pulmonary Venous and Atrial Septal Anatomy
  3. Look for associations (See next card)
61
Q

Cor triatriatum dexter

What 3 things is associated with this disorder?

A
  1. ASD
  2. MR
  3. Persistent LSVC
62
Q

What is seen here?

A

Cor triatriatum sinister

(Top dorsal chamber receives pulmonary blood flow)

(Bottom ventral chamber with green arrow = LAA and MV located here

63
Q

Cor triatriatum sinister causes what potential problem?

A

LV inlet obstruction leading to mitral stenosis

64
Q

Why is cor triatriatum sinister a surgical dilemma if found incidentally?

A

Exposes patient to risk of open-chamber procedure

65
Q

What can Cor triatriatum dexter be confused with?

A

Eustachian Valve (separates during cardiac cycle)

66
Q

Identify numbers 1

A

1 = Pectinate Muscles

67
Q

Identify number 2 in the image

A

2 = Crista Terminalis

68
Q

Identify 3 in the image

A

Right Atrial Appendage

69
Q

How many lobes does the LAA of a normal human heart consist of?

A

Can have 1-4

1 = 20%

2 = 54%

3 = 23%

4 = 3%

70
Q

Why is there a risk of stroke after cardioversion even if the appendage is clean?

A

Atrium is stunned and stroke risk still possible for 10 days

71
Q

What can lipomatous hypertrophy be associated with?

A

Atrial Arrythmias

72
Q

In addition to empyting velocities, what can left atrial thrombi be associated with?

A

Spontaneous Echo contrast

73
Q

What is the Virchow Triad?

A
  1. Stasis
  2. Endothelial Dysfunction
  3. Hypercoaguloable state
74
Q

What is seen in the image here?

A

chiari network

75
Q

Where does the chiari network originate?

A

Eustachian Valve

76
Q

What are chiari networks associated with? (2 things)

A
  1. PFO
  2. Atrial Septal Aneurysm
77
Q

What can Chiari networks be involved in the pathogenesis of?

(3 things)

A
  1. Thromboembolic disease
  2. Arrythmias
  3. Entrapment of percutaneous devices
78
Q

What is the Eustachian Valve a remnant of?

A

Embryological Remnant of Sinus Venosus

79
Q

What exactly is the chiari network?

A

Fibrous reticulum with multiple threads inserting onto the anterior surface of the Eustachian valve, posterior wall of the ostium of the IVC as well as the crista terminalis

80
Q

What is the most common cause of thrombi of the RV?

A

Peripheral vein thrombus or indwelling catheter

81
Q

What echo modality is better to image LV thrombus:

TTE or TEE?

A

TTE more sensitive

82
Q

What does the moderator band carry?

A

The moderator band is important because it carries part of the right bundle branch of the atrioventricular bundle of the conduction system of the heart to the anterior papillary muscle.

This shortcut across the chamber of the ventricle ensures equal conduction time in the left and right ventricles, allowing for coordinated contraction of the anterior papillary muscle.

83
Q

What is seen here in the LV?

A

False Tendon

84
Q

What are false tendons?

A

Fibrous muscular bands stretching across the LV from ventricular septum to papillary muscle or LV free wall

No connection to vaalves

Single/Multiple

85
Q

Are false tendons clinically significant?

A

No

86
Q

What is seen in this image?

A

Right Atrial Appendage Thrombus

87
Q

If you have a Right Atrial Appendage clot, what do you need to tell the surgeon

A

Recommend a different venous cannulation site

(Standard bicaval cannulation could dislodge the thrombus)

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