TUMOUR MARKERS AND CANCER OF UNKNOWN PRIMARY Flashcards Preview

ONCOLOGY AND PALLIATIVE CARE > TUMOUR MARKERS AND CANCER OF UNKNOWN PRIMARY > Flashcards

Flashcards in TUMOUR MARKERS AND CANCER OF UNKNOWN PRIMARY Deck (12):
1

What is the tumour marker for hepatocellular carcinoma?

Alpha fetoprotein

Also tumour marker for germ cell tumour (would have high hCG too)

2

What are the tumour markers for pancreatic cancer?

Ca 19-9

Limited specificity

(Also Tumour M2-PK)

3

What is the tumour marker for ovarian cancer?

Ca-125

4

What are the tumour markers for germ cell tumours?

Alpha fetoprotein

hCG

5

What is the tumour marker for prostate cancer?

PSA

6

What is the tumour marker for colorectal cancer?

CEA (Carcinoembryonic antigen)

Low specificity

7

What cancer(s) is alpha fetoprotein (AFP) a tumour marker for?

Hepatocellular carcinoma

Germ cell tumours

8

What cancer(s) is PSA a tumour marker for?

Prostate cancer

9

What cancer(s) is CEA a tumour marker for?

Colorectal cancer - mainly

Cervical cancer

Lung cancer

Ovarian cancer

Breast cancer

Urinary tract cancer

10

What cancer(s) is Ca 19-9 a tumour marker for?

Pancreatic cancer - mainly

Colorectal

GI

11

What investigations would you do for someone who presents with signs of cancer of unknown primary?

Chest X-ray

Tumour markers

Myeloma screen - if there are lytic bone lesions

Endoscopy - if there are symptoms

PET scan


Remember that we perform investigations only if:

– the results are likely to affect a treatment decision

– the patient understands why the investigations are being carried out

– the patient understands the potential benefits and risks of investigation and treatment and

– the patient is prepared to accept treatment

12

What are the different levels of performance status with regard to cancer patients?

0 - Fully active, able to carry on all pre-disease performance without restriction

1 - Restricted in physically strenuous activity but ambulatory and able to carry out light work

2 - Ambulatory, unable to carry out any work activities, up and about more than 50% of waking hours

3 - Capable of only limited self care, confined to bed or chair more than 50% of waking hours

4 - Completely disabled, totally confined to bed or chair